“ROBO-TRIPPING”: DEXTROMETHORPHAN ABUSE AND ITS ANESTHETIC IMPLICATIONS, CASE REPORT

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LINN KELLY A.; LONG MICAH T.; PAGEL PAUL S.

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Journal: Anesthesiology and Pain Medicine Year:2014 | Volume:4 | Issue:5 Page(s): 1-4

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Title

“ROBO-TRIPPING”: DEXTROMETHORPHAN ABUSE AND ITS ANESTHETIC IMPLICATIONS, CASE REPORT

Author(s)

LINN KELLY A. | LONG MICAH T. | PAGEL PAUL S. | Issue Writer Certificate

Keywords

DEXTROMETHORPHAN

SIGMA OPIOID RECEPTOR

SUBSTANCE ABUSE

ADDICTION

DISSOCIATIVE ANESTHESIA

NMDA RECEPTOR ANTAGONISTS

Abstract

Introduction: We describe a patient scheduled for elective surgery who regularly consumed approximately 12 to 15 times the maximum recommended daily dose of DEXTROMETHORPHAN. We describe the clinical pharmacology of DEXTROMETHORPHAN and discuss its anesthetic implications.Case Presentation: A 30-year-old man with a history of a nasal fracture was scheduled to undergo an elective septorhinoplasty. He reported daily consumption of large quantities (1440 to 1800 mg) of DEXTROMETHORPHAN for six years. He was previously treated for DEXTROMETHORPHAN dependency on several occasions with urine DEXTROMETHORPHAN levels exceeding 2000 ng/mL. He described marked dissociative effects when abusing the drug, but had abstained from use for 48 hours before his elective surgery. Considering that DEXTROMETHORPHAN has a relatively short half-life and that the patient did not suffer major withdrawal symptoms after voluntarily discontinuing the drug, the authors proceeded with the case while recognizing that the drug has significant neuropsychiatric and sympathetic nervous system stimulant effects resulting from its actions as a N-methyl-D-aspartate receptor antagonist.Conclusions: Anesthesiologists need to be aware of DEXTROMETHORPHAN’s clinical pharmacology because recreational abuse of the drug has become increasingly common in adolescents and young adults.

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APA: Copy

LINN, KELLY A., LONG, MICAH T., & PAGEL, PAUL S.. (2014). “ROBO-TRIPPING”: DEXTROMETHORPHAN ABUSE AND ITS ANESTHETIC IMPLICATIONS, CASE REPORT. ANESTHESIOLOGY AND PAIN MEDICINE, 4(5), 1-4. SID. https://sid.ir/paper/328523/en

Vancouver: Copy

LINN KELLY A., LONG MICAH T., PAGEL PAUL S.. “ROBO-TRIPPING”: DEXTROMETHORPHAN ABUSE AND ITS ANESTHETIC IMPLICATIONS, CASE REPORT. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2014;4(5):1-4. Available from: https://sid.ir/paper/328523/en

IEEE: Copy

KELLY A. LINN, MICAH T. LONG, and PAUL S. PAGEL, ““ROBO-TRIPPING”: DEXTROMETHORPHAN ABUSE AND ITS ANESTHETIC IMPLICATIONS, CASE REPORT,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 4, no. 5, pp. 1–4, 2014, [Online]. Available: https://sid.ir/paper/328523/en

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