IMPACT OF VITAMIN C SUPPLEMENTATION ON POST-CARDIAC SURGERY ICU AND HOSPITAL LENGTH OF STAY

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SADEGHPOUR ANITA; ALIZADEHASL AZIN; KYAVAR MAJID; SADEGHI TAHEREH; MOLUDI JALAL; GHOLIZADEH FARHAD; TOTONCHI ZIAE; GHADRDOOST BEHSHID

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Journal: Anesthesiology and Pain Medicine Year:2015 | Volume:5 | Issue:1 Page(s): 1-5

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Title

IMPACT OF VITAMIN C SUPPLEMENTATION ON POST-CARDIAC SURGERY ICU AND HOSPITAL LENGTH OF STAY

Author(s)

Keywords

VITAMIN C

ANTIOXIDANT

INTENSIVE CARE UNIT

HOSPITAL STAY

ATRIAL FIBRILLATION

Abstract

Background: Prolonged INTENSIVE CARE UNIT (ICU) and HOSPITAL STAY after cardiac surgery is vitally important and is influenced by both intraoperative and postoperative factors.Objectives: This randomized clinical trial study was designed to assess whether VITAMIN C supplementation could reduce the length of ICU and HOSPITAL STAY in post-cardiac surgery patients.Patients and Methods: Two hundred and ninety patients scheduled for adult cardiac surgery including coronary, valve and congenital operations were randomized into two groups: an intervention group, who received 2 g of VITAMIN C (ascorbic acid) intravenously, immediately before surgery in the operating theatre, followed by 1 g daily oral doses for the first 4 postoperative days; and a placebo group, who received an equal number of identical tablets in the same shape and size.Results: Hospital length of stay was significantly different between the two groups (10.17± .63 days in the intervention group vs. 12±4.51 days in the placebo group; P=0.01), while there was no significant difference in the ICU stay between the groups (3.42±1.06 days in intervention group vs. 3.43±1.09 days in the placebo group; P=0.88). There were significant differences in the intubation time and the drainage volume in the ICU and the first 24 postoperative hours between the two groups (P for both=0.003).Conclusions: VITAMIN C can decrease the length of HOSPITAL STAY, drainage volume in the ICU and in the first 24 postoperative hours, intubation time and some complications in patients after cardiac surgery; perhaps by decreasing inflammatory factors.

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APA: Copy

SADEGHPOUR, ANITA, ALIZADEHASL, AZIN, KYAVAR, MAJID, SADEGHI, TAHEREH, MOLUDI, JALAL, GHOLIZADEH, FARHAD, TOTONCHI, ZIAE, & GHADRDOOST, BEHSHID. (2015). IMPACT OF VITAMIN C SUPPLEMENTATION ON POST-CARDIAC SURGERY ICU AND HOSPITAL LENGTH OF STAY. ANESTHESIOLOGY AND PAIN MEDICINE, 5(1), 1-5. SID. https://sid.ir/paper/328550/en

Vancouver: Copy

SADEGHPOUR ANITA, ALIZADEHASL AZIN, KYAVAR MAJID, SADEGHI TAHEREH, MOLUDI JALAL, GHOLIZADEH FARHAD, TOTONCHI ZIAE, GHADRDOOST BEHSHID. IMPACT OF VITAMIN C SUPPLEMENTATION ON POST-CARDIAC SURGERY ICU AND HOSPITAL LENGTH OF STAY. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2015;5(1):1-5. Available from: https://sid.ir/paper/328550/en

IEEE: Copy

ANITA SADEGHPOUR, AZIN ALIZADEHASL, MAJID KYAVAR, TAHEREH SADEGHI, JALAL MOLUDI, FARHAD GHOLIZADEH, ZIAE TOTONCHI, and BEHSHID GHADRDOOST, “IMPACT OF VITAMIN C SUPPLEMENTATION ON POST-CARDIAC SURGERY ICU AND HOSPITAL LENGTH OF STAY,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 5, no. 1, pp. 1–5, 2015, [Online]. Available: https://sid.ir/paper/328550/en

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