PROTECTIVE EFFECT OF MICROPOROUS NATURAL CLINOPTILOLITE ON LEAD-INDUCED LEARNING AND MEMORY IMPAIRMENT IN RATS

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NIKPEY AHMAD; KAZEMIAN HOSSEIN; SAFARI VARYANI ALI; REZAIE MARJAN; SIRATI SABET MAJID

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Journal: Health Scope Year:2013 | Volume:2 | Issue:1 Page(s): 52-57

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Title

PROTECTIVE EFFECT OF MICROPOROUS NATURAL CLINOPTILOLITE ON LEAD-INDUCED LEARNING AND MEMORY IMPAIRMENT IN RATS

Author(s)

Keywords

LEAD POISONING

ZEOLITES

CLINOPTILOLITE

RATS

Abstract

Background: LEAD POISONING impairs memory and learning.Objectives: The protective effect of natural zeolite CLINOPTILOLITE on memory and learning impairment in RATS exposed to lead acetate was investigated.Materials and Methods: 60 male Wistar RATS in six groups treated for 2 months with diets contained different ratios of natural zeolite (i.e.5% or 12.5%), and %0.2 lead acetate (LA) concentrations. behavioral test was evaluated by passive avoidance learning method in shuttle box at 6, 12, 24, 48 hours, and one week after the shock test.Results: digestive exposure with 0.2% lead acetate in the presence of zeolite additive had no effect on the RATS’ memory performance (P & lt; 0.05). Adding 5 and 12.5%w/w of natural zeolite to the RATS’ feed improved short-term, medium-term, and long-term memory performance (P & lt; 0.05) compared to the control group.Conclusion: observed improvement in memory function can be considered in part as the indirect effects of cation exchange or adsorption property of ZEOLITES.

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APA: Copy

NIKPEY, AHMAD, KAZEMIAN, HOSSEIN, SAFARI VARYANI, ALI, REZAIE, MARJAN, & SIRATI SABET, MAJID. (2013). PROTECTIVE EFFECT OF MICROPOROUS NATURAL CLINOPTILOLITE ON LEAD-INDUCED LEARNING AND MEMORY IMPAIRMENT IN RATS. HEALTH SCOPE, 2(1), 52-57. SID. https://sid.ir/paper/330341/en

Vancouver: Copy

NIKPEY AHMAD, KAZEMIAN HOSSEIN, SAFARI VARYANI ALI, REZAIE MARJAN, SIRATI SABET MAJID. PROTECTIVE EFFECT OF MICROPOROUS NATURAL CLINOPTILOLITE ON LEAD-INDUCED LEARNING AND MEMORY IMPAIRMENT IN RATS. HEALTH SCOPE[Internet]. 2013;2(1):52-57. Available from: https://sid.ir/paper/330341/en

IEEE: Copy

AHMAD NIKPEY, HOSSEIN KAZEMIAN, ALI SAFARI VARYANI, MARJAN REZAIE, and MAJID SIRATI SABET, “PROTECTIVE EFFECT OF MICROPOROUS NATURAL CLINOPTILOLITE ON LEAD-INDUCED LEARNING AND MEMORY IMPAIRMENT IN RATS,” HEALTH SCOPE, vol. 2, no. 1, pp. 52–57, 2013, [Online]. Available: https://sid.ir/paper/330341/en

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