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Information Journal Paper

Title

SENSITIVITY AND SPECIFICITY OF ELISA TEST IN DIAGNOSIS OF BRUCELLOSIS

Pages

  95-98

Abstract

 Aims: BRUCELLOSIS is a common disease with different clinical forms and diagnostic methods. Regarding to the increasing use of ELISA TEST as a new diagnostic method and differences between the results of standard ELISA and agglutination tests, this study was conducted to determine the SENSITIVITY and SPECIFICITY of ELISA method for diagnosis of BRUCELLOSIS.Materials & Methods: This cross-sectional study was done in Kashan, Iran in 2007, on 457 blood samples of persons with clinically suspected BRUCELLOSIS who were referred to laboratory by infectious disease’ specialist and on 50 individuals without history of BRUCELLOSIS as the control group. The wright, coombs wright and 2ME tests as the standard tests and ELISA IgG and IgM were done and characteristic and SENSITIVITY of ELISA was compared with standard tests and the results were presented as the descriptive statistics. Results: The SENSITIVITY of IgG and IgM ELISA TESTs was 93.7% and 12.5%, respectively. IgG and IgM ELISA TEST’s SPECIFICITY was 70.6% and 100%, the positive predictive value of IgG and IgM ELISA TESTs was 19.4% and 100%, respectively and the negative predictive value of ELISA IgG and IgM was 99.3% and 94%.Conclusion: Regarding the high SENSITIVITY of IgG ELISA and high SPECIFICITY of IgM ELISA, the ELISA TEST can be used along with agglutination tests for diagnosis of BRUCELLOSIS.

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    Cite

    APA: Copy

    VAKILI, Z., MOUMEN HERAVI, M., SHARIF, A.R., & MASOUMI, MARYAM. (2010). SENSITIVITY AND SPECIFICITY OF ELISA TEST IN DIAGNOSIS OF BRUCELLOSIS. KOWSAR MEDICAL JOURNAL, 15(2), 95-98. SID. https://sid.ir/paper/33056/en

    Vancouver: Copy

    VAKILI Z., MOUMEN HERAVI M., SHARIF A.R., MASOUMI MARYAM. SENSITIVITY AND SPECIFICITY OF ELISA TEST IN DIAGNOSIS OF BRUCELLOSIS. KOWSAR MEDICAL JOURNAL[Internet]. 2010;15(2):95-98. Available from: https://sid.ir/paper/33056/en

    IEEE: Copy

    Z. VAKILI, M. MOUMEN HERAVI, A.R. SHARIF, and MARYAM MASOUMI, “SENSITIVITY AND SPECIFICITY OF ELISA TEST IN DIAGNOSIS OF BRUCELLOSIS,” KOWSAR MEDICAL JOURNAL, vol. 15, no. 2, pp. 95–98, 2010, [Online]. Available: https://sid.ir/paper/33056/en

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