مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

341
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

93
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

1

Information Journal Paper

Title

EFFECTS OF PLATELET-RICH PLASMA ON CARTILAGE GRAFTS IN RABBITS AS AN ANIMAL MODEL

Pages

  91-98

Abstract

 BACKGROUND: CARTILAGE tissue has limited regenerative capacity and the management of CARTILAGE defects has always been a challenging issue.Platelet-rich plasma (PRP) has been recently been used to improve healing of CARTILAGE defects. In the present experiment, we aimed to investigate the effects of PRP on REGENERATION capacity as well as survival of the CARTILAGE GRAFTs in a RABBIT model.METHODS: In 15 white New Zealand RABBITs, auricular CARTILAGE was used to produce 4 pieces of CARTILAGE (each about 2×2 cm). Two samples were diced to small pieces and 2 samples left intact.PRP was prepared using 5 ml of auricular blood. After measuring of the weight and volume of CARTILAGEs, they mixed with either normal saline or PRP and then implanted on the back of the RABBIT. After 12 weeks, the implants were removed and the weight and volume were measured and the numbers of nucleated lacunae were counted on H & E staining.RESULTS: Histological findings showed that in both the intact and diced CARTILAGEs, adding PRP resulted in increasing REGENERATION of chondrocytes. Moreover, adding PRP to intact CARTILAGEs had a significant effect in maintaining the GRAFTs ‘weight and volume (p<0.05) but in diced CARTILAGEs, this effect was not significant.CONCLUSION: Our findings yielded valuable information on the effect of PRP on survival and REGENERATION of autologous CARTILAGE GRAFTs as the extent of angiogenesis and the diameters of vessels were more pronounced in the side using PRP and markedly lesser reduction of weight and volume were visible in this group. PRP was effective in increasing survival and REGENERATION capacity of CARTILAGE GRAFTs in RABBIT model.

Cites

References

  • No record.

    • Cite

    APA: Copy

    MANAFI, ALI, KAVIANI FAR, KAMRAN, MORADI, MASOUD, MANAFI, AMIR, & MANAFI, FARZAD. (2012). EFFECTS OF PLATELET-RICH PLASMA ON CARTILAGE GRAFTS IN RABBITS AS AN ANIMAL MODEL. WORLD JOURNAL OF PLASTIC SURGERY, 1(2), 91-98. SID. https://sid.ir/paper/331081/en

    Vancouver: Copy

    MANAFI ALI, KAVIANI FAR KAMRAN, MORADI MASOUD, MANAFI AMIR, MANAFI FARZAD. EFFECTS OF PLATELET-RICH PLASMA ON CARTILAGE GRAFTS IN RABBITS AS AN ANIMAL MODEL. WORLD JOURNAL OF PLASTIC SURGERY[Internet]. 2012;1(2):91-98. Available from: https://sid.ir/paper/331081/en

    IEEE: Copy

    ALI MANAFI, KAMRAN KAVIANI FAR, MASOUD MORADI, AMIR MANAFI, and FARZAD MANAFI, “EFFECTS OF PLATELET-RICH PLASMA ON CARTILAGE GRAFTS IN RABBITS AS AN ANIMAL MODEL,” WORLD JOURNAL OF PLASTIC SURGERY, vol. 1, no. 2, pp. 91–98, 2012, [Online]. Available: https://sid.ir/paper/331081/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button