SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF CERTAIN NOVEL ARYL HYDRAZONE PYRAZOLINE-5-ONES CONTAINING THIAZOLE MOIETY

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REDDY DASTAGIRI REDDY MALIKI; GURU PRASAD ALURU RAGHAVENDRA; NARASIMHA SPOORTHY YADATI; KRISHNA RAO RAVINDRANATH LAKSHMANA RAO

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Journal: Advanced Pharmaceutical Bulletin Year:2013 | Volume:3 | Issue:1 Page(s): 153-159

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Title

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF CERTAIN NOVEL ARYL HYDRAZONE PYRAZOLINE-5-ONES CONTAINING THIAZOLE MOIETY

Author(s)

REDDY DASTAGIRI REDDY MALIKI | GURU PRASAD ALURU RAGHAVENDRA | NARASIMHA SPOORTHY YADATI | KRISHNA RAO RAVINDRANATH LAKSHMANA RAO | Issue Writer Certificate

Keywords

PYRAZOLINE-5-ONES

THIAZOLE

SYNTHESIS

ELEMENTAL ANALYSIS

SPECTRAL ANALYSIS

ANTIMICROBIAL ACTIVITY

Abstract

Purpose: The aim of this article is to synthesize, characterize and evaluate the ANTIMICROBIAL ACTIVITY of certain novel 3-methyl-5-oxo-4- (phenyl hydrazono) -4, 5-dihydro-pyrazol-1-yl] -acetic acid N|- (4-substituted thiazol-2-yl) -hydrazides.Methods: The synthesized compounds were characterized by ELEMENTAL ANALYSIS and IR, NMR and mass spectral data. The ANTIMICROBIAL ACTIVITY of novel compounds was evaluated by broth dilution method.Results: XVe, XVf and XVg have shown better antibacterial activity than other compounds of the series. XVa, XVc, XVd and XVe have shown better antifungal activity than the other compounds of the series.Conclusion: All compounds were found to exhibit fair degree of ANTIMICROBIAL ACTIVITY.

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APA: Copy

REDDY DASTAGIRI REDDY, MALIKI, GURU PRASAD, ALURU RAGHAVENDRA, NARASIMHA SPOORTHY, YADATI, & KRISHNA RAO RAVINDRANATH, LAKSHMANA RAO. (2013). SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF CERTAIN NOVEL ARYL HYDRAZONE PYRAZOLINE-5-ONES CONTAINING THIAZOLE MOIETY. ADVANCED PHARMACEUTICAL BULLETIN, 3(1), 153-159. SID. https://sid.ir/paper/331680/en

Vancouver: Copy

REDDY DASTAGIRI REDDY MALIKI, GURU PRASAD ALURU RAGHAVENDRA, NARASIMHA SPOORTHY YADATI, KRISHNA RAO RAVINDRANATH LAKSHMANA RAO. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF CERTAIN NOVEL ARYL HYDRAZONE PYRAZOLINE-5-ONES CONTAINING THIAZOLE MOIETY. ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2013;3(1):153-159. Available from: https://sid.ir/paper/331680/en

IEEE: Copy

MALIKI REDDY DASTAGIRI REDDY, ALURU RAGHAVENDRA GURU PRASAD, YADATI NARASIMHA SPOORTHY, and LAKSHMANA RAO KRISHNA RAO RAVINDRANATH, “SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF CERTAIN NOVEL ARYL HYDRAZONE PYRAZOLINE-5-ONES CONTAINING THIAZOLE MOIETY,” ADVANCED PHARMACEUTICAL BULLETIN, vol. 3, no. 1, pp. 153–159, 2013, [Online]. Available: https://sid.ir/paper/331680/en

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