SHORT COMMUNICATION: STUDY OF THERMAL ANALYSIS BEHAVIOR OF FENBENDAZOLE AND RAFOXANIDE

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KAMAL ATTIA ALI; SAYED SAAD AHMED; SAMI ALARAKI MANAL; SAAD ELZANFALY EMAN

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Journal: Advanced Pharmaceutical Bulletin Year:2017 | Volume:7 | Issue:2 Page(s): 329-334

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Title

SHORT COMMUNICATION: STUDY OF THERMAL ANALYSIS BEHAVIOR OF FENBENDAZOLE AND RAFOXANIDE

Author(s)

KAMAL ATTIA ALI | SAYED SAAD AHMED | SAMI ALARAKI MANAL | SAAD ELZANFALY EMAN | Issue Writer Certificate

Keywords

FENBENDAZOLE

RAFOXANIDE

THERMAL ANALYSIS

PURITY

MOLECULAR ORBITAL CALCULATIONS

Abstract

Purpose: THERMAL ANALYSIS techniques have been applied to study the thermal behavior of FENBENDAZOLE (Fen) and RAFOXANIDE (Raf). Semi-empirical MOLECULAR ORBITAL CALCULATIONS were used to confirm these results.Methods: Thermogravimetric analysis, derivative thermogravimetry, differential THERMAL ANALYSIS and differential scanning calorimetry were used to determine the thermal behavior and PURITY of the drugs under investigation.Results: Thermal behavior of Fen and Raf were augmented using semi-empirical MOLECULAR ORBITAL CALCULATIONS. The PURITY values were found to be 99.17% and 99.60% for Fen and Raf, respectively.Conclusion: THERMAL ANALYSIS techniques gave satisfactory results to obtain quality control parameters such as melting point and degree of PURITY at low cost, furthermore, its simplicity and sensitivity justifies its application in quality control laboratories.

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References

THERMAL ANALYSIS INVESTIGATION OF DAPOXETINE AND VARDENAFIL HYDROCHLORIDES USING MOLECULAR ORBITAL CALCULATIONS

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APA: Copy

KAMAL ATTIA, ALI, SAYED SAAD, AHMED, SAMI ALARAKI, MANAL, & SAAD ELZANFALY, EMAN. (2017). SHORT COMMUNICATION: STUDY OF THERMAL ANALYSIS BEHAVIOR OF FENBENDAZOLE AND RAFOXANIDE. ADVANCED PHARMACEUTICAL BULLETIN, 7(2), 329-334. SID. https://sid.ir/paper/331875/en

Vancouver: Copy

KAMAL ATTIA ALI, SAYED SAAD AHMED, SAMI ALARAKI MANAL, SAAD ELZANFALY EMAN. SHORT COMMUNICATION: STUDY OF THERMAL ANALYSIS BEHAVIOR OF FENBENDAZOLE AND RAFOXANIDE. ADVANCED PHARMACEUTICAL BULLETIN[Internet]. 2017;7(2):329-334. Available from: https://sid.ir/paper/331875/en

IEEE: Copy

ALI KAMAL ATTIA, AHMED SAYED SAAD, MANAL SAMI ALARAKI, and EMAN SAAD ELZANFALY, “SHORT COMMUNICATION: STUDY OF THERMAL ANALYSIS BEHAVIOR OF FENBENDAZOLE AND RAFOXANIDE,” ADVANCED PHARMACEUTICAL BULLETIN, vol. 7, no. 2, pp. 329–334, 2017, [Online]. Available: https://sid.ir/paper/331875/en

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