LACK OF ASSOCIATION BETWEEN MIRNA-146A RS2910164 AND MIRNA-499 RS3746444 GENE POLYMORPHISMS AND SUSCEPTIBILITY TO PULMONARY TUBERCULOSIS

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NADERI MOHAMMAD; HASHEMI MOHAMMAD; KHORGAMI PARISA; KOSHKI MALIHEH; EBRAHIMI MAHBOUBEH; AMININIA SHADI; SHARIFI MOOD BATOOL; TAHERI MOHSEN

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Journal: International Journal of Molecular and Cellular Medicine Year:2015 | Volume:4 | Issue:1 Page(s): 40-45

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Title

LACK OF ASSOCIATION BETWEEN MIRNA-146A RS2910164 AND MIRNA-499 RS3746444 GENE POLYMORPHISMS AND SUSCEPTIBILITY TO PULMONARY TUBERCULOSIS

Author(s)

Keywords

TUBERCULOSIS

MICRORNA

MIRNA-146A

MIRNA-499

POLYMORPHISM

Abstract

Single-nucleotide POLYMORPHISMs (SNPs) in miRNAsmay alter its expression levels or processing and contribute to susceptibility to a wide range of diseases. Our study aimed to evaluate the possible association between MIRNA-146A rs2910164 and MIRNA-499 rs3746444 POLYMORPHISMs and susceptibility to pulmonary TUBERCULOSIS (PTB) in a sample of Iranian population. This case- control study was performed on 202 PTB patients and 204 healthy individuals. Genotyping was performed using tetra amplification refractory mutation system-polymerase chain reaction (T-ARMS-PCR). The results indicated that neither MIRNA-499 rs3746444 nor MIRNA-146A rs2910164 are associated with the risk of PTB in a sample of Iranian population. Larger studies with different ethnicities are required to validate our findings.

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APA: Copy

NADERI, MOHAMMAD, HASHEMI, MOHAMMAD, KHORGAMI, PARISA, KOSHKI, MALIHEH, EBRAHIMI, MAHBOUBEH, AMININIA, SHADI, SHARIFI MOOD, BATOOL, & TAHERI, MOHSEN. (2015). LACK OF ASSOCIATION BETWEEN MIRNA-146A RS2910164 AND MIRNA-499 RS3746444 GENE POLYMORPHISMS AND SUSCEPTIBILITY TO PULMONARY TUBERCULOSIS. INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, 4(1), 40-45. SID. https://sid.ir/paper/332149/en

Vancouver: Copy

NADERI MOHAMMAD, HASHEMI MOHAMMAD, KHORGAMI PARISA, KOSHKI MALIHEH, EBRAHIMI MAHBOUBEH, AMININIA SHADI, SHARIFI MOOD BATOOL, TAHERI MOHSEN. LACK OF ASSOCIATION BETWEEN MIRNA-146A RS2910164 AND MIRNA-499 RS3746444 GENE POLYMORPHISMS AND SUSCEPTIBILITY TO PULMONARY TUBERCULOSIS. INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE[Internet]. 2015;4(1):40-45. Available from: https://sid.ir/paper/332149/en

IEEE: Copy

MOHAMMAD NADERI, MOHAMMAD HASHEMI, PARISA KHORGAMI, MALIHEH KOSHKI, MAHBOUBEH EBRAHIMI, SHADI AMININIA, BATOOL SHARIFI MOOD, and MOHSEN TAHERI, “LACK OF ASSOCIATION BETWEEN MIRNA-146A RS2910164 AND MIRNA-499 RS3746444 GENE POLYMORPHISMS AND SUSCEPTIBILITY TO PULMONARY TUBERCULOSIS,” INTERNATIONAL JOURNAL OF MOLECULAR AND CELLULAR MEDICINE, vol. 4, no. 1, pp. 40–45, 2015, [Online]. Available: https://sid.ir/paper/332149/en

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