CHARACTERIZATION OF THE EXTENDED-SPECTRUM BETA-LACTAMASE PRODUCERS AMONG NON- FERMENTING GRAM-NEGATIVE BACTERIA ISOLATED FROM BURNT PATIENTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HAKEMI VALA MOJDEH; HALLAJZADEH MASOUMEH; FALLAH FATEMEH; HASHEMI ALI; GOUDARZI HOSSEIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: ARCHIVE OF HYGIENE SCIENCES Year:2013 | Volume:2 | Issue:1 Page(s): 1-6

Download Full-Text

View:

435

Download:

172

Cites:

Information Journal Paper

Title

CHARACTERIZATION OF THE EXTENDED-SPECTRUM BETA-LACTAMASE PRODUCERS AMONG NON- FERMENTING GRAM-NEGATIVE BACTERIA ISOLATED FROM BURNT PATIENTS

Author(s)

Keywords

ACINETOBACTER BAUMANNI BETA-LACTAMASES DRUG RESISTANCE IRAN PATIENTS

BURNT PSEUDOMONAS AERUGINOSA

Abstract

Background & Aims of the Study: Extended-spectrum beta-Lactamases (ESBLs) represent a major group of beta-lactamases which are responsible for resistance to oxyiminocephalosporins and aztreonam and currently being identified in large numbers throughout the world. The objective of this study was to characterize ESBL producers among nonfermenter gram-negative bacteria isolated from burnt patients.Materials & Methods: During April to July 2012, 75 non-fermenter gram-negative bacilli were isolated from 240 bacterial cultures collected from wounds of burnt patients admitted to the Burn Unit at Shahid Motahari Hospital (Tehran, Iran). Bacterial isolation and identification was done using standard methods. Antimicrobial susceptibility testing was performed by disk diffusion method for all strains against selected antibiotics and minimum inhibitory concentration was determined by microdilution test. The ability to produce ESBL was detected through double disk synergy test among candidate strains.Results: Of 75 non-fermenter isolates, 47 Pseudomonas aeruginosa and 28 Acinetobacter baumanniiwere identified. The resistance of P. aeruginosa isolates to tested antibiotics in antibiogram test were 100% to cefpodoxime, 82.98% to ceftriaxone, 78.73% to imipenem, 75% to meropenem, 72.72% to gentamicin, 69.23% to ciprofloxacin and aztreonam, 67.57% to cefepime, 65.95% to ceftazidime, and 61.53% to piperacillin. The results for Acinetobacter baumanniiwere 100% to ceftazidime, cefepime, ciprofloxacin, imipenem, meropenem, cefpodoxime, and cefotaxim, 96.85% to gentamicin, 89.65% to ceftriaxone, 65.51% to aztreonam, and 40% to piperacillin. Double disk synergy test showed that 21 (28%) of non-fermenter isolates were ESBL producer.Conclusions: None of the third or fourth generation of cephalosporins is suitable for treatment ofPseudomonas aeruginosa and Acinetobacter baumannii isolated from burnt patients.

Cites

No record.

References

No record.

Cite

APA: Copy

HAKEMI VALA, MOJDEH, HALLAJZADEH, MASOUMEH, FALLAH, FATEMEH, HASHEMI, ALI, & GOUDARZI, HOSSEIN. (2013). CHARACTERIZATION OF THE EXTENDED-SPECTRUM BETA-LACTAMASE PRODUCERS AMONG NON- FERMENTING GRAM-NEGATIVE BACTERIA ISOLATED FROM BURNT PATIENTS. ARCHIVE OF HYGIENE SCIENCES, 2(1), 1-6. SID. https://sid.ir/paper/333003/en

Vancouver: Copy

HAKEMI VALA MOJDEH, HALLAJZADEH MASOUMEH, FALLAH FATEMEH, HASHEMI ALI, GOUDARZI HOSSEIN. CHARACTERIZATION OF THE EXTENDED-SPECTRUM BETA-LACTAMASE PRODUCERS AMONG NON- FERMENTING GRAM-NEGATIVE BACTERIA ISOLATED FROM BURNT PATIENTS. ARCHIVE OF HYGIENE SCIENCES[Internet]. 2013;2(1):1-6. Available from: https://sid.ir/paper/333003/en

IEEE: Copy

MOJDEH HAKEMI VALA, MASOUMEH HALLAJZADEH, FATEMEH FALLAH, ALI HASHEMI, and HOSSEIN GOUDARZI, “CHARACTERIZATION OF THE EXTENDED-SPECTRUM BETA-LACTAMASE PRODUCERS AMONG NON- FERMENTING GRAM-NEGATIVE BACTERIA ISOLATED FROM BURNT PATIENTS,” ARCHIVE OF HYGIENE SCIENCES, vol. 2, no. 1, pp. 1–6, 2013, [Online]. Available: https://sid.ir/paper/333003/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops