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Information Journal Paper

Title

THE EFFECTS OF HUMAN AMNIOTIC MEMBRANE ON HEALING OF COLONIC ANASTOMOSIS IN DOGS

Pages

  97-100

Abstract

 Background: Anastomotic leakage is claimed to be responsible for about one third of deaths following COLON surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention.Objectives: This study was conducted to determine surgical and histological outcomes of applying human amniotic membrane (HAM) in COLONic anastomosis in dogs.Materials and Methods: Eight cross breed male dogs were divided into two equal groups. After anesthesia and exploration, 5cm of left COLON was resected, and end to end anastomosis was performed in a single layer. In the treatment group (B), HAM patch measuring 2×3 cm was wrapped around the anastomotic line. Mann-Whitney U test was used to compare the results in the two groups due to small sample size, and normal distribution of data was examined using the Kolmogorov simirnov test (P=0.03).Results: Modified scoring system for surgical wound healing was used to identify the grade of healing in all samples. The healing score was significantly higher in the HAM group (P=0.01).Conclusions: HAM plays a positive role in healing of COLONic anastomosis, and would lead to better histological outcomes compared to simple anastomosis in dogs.

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    APA: Copy

    NAJIBPOUR, NEDA, JAHANTAB, MOHAMMAD BAGHER, HOSSEINZADEH, MASSOOD, ROSHANRAVAN, REZA, MOSLEMI, SAM, RAHIMI KAZEROONI, SALAR, SAFARPOUR, ALIREZA, GHAHRAMANI, LEILA, & HOSSEINI, SEYED VAHID. (2013). THE EFFECTS OF HUMAN AMNIOTIC MEMBRANE ON HEALING OF COLONIC ANASTOMOSIS IN DOGS. IRANIAN JOURNAL OF COLORECTAL RESEARCH (ANNALS OF COLORECTAL RESEARCH), 1(3), 97-100. SID. https://sid.ir/paper/334944/en

    Vancouver: Copy

    NAJIBPOUR NEDA, JAHANTAB MOHAMMAD BAGHER, HOSSEINZADEH MASSOOD, ROSHANRAVAN REZA, MOSLEMI SAM, RAHIMI KAZEROONI SALAR, SAFARPOUR ALIREZA, GHAHRAMANI LEILA, HOSSEINI SEYED VAHID. THE EFFECTS OF HUMAN AMNIOTIC MEMBRANE ON HEALING OF COLONIC ANASTOMOSIS IN DOGS. IRANIAN JOURNAL OF COLORECTAL RESEARCH (ANNALS OF COLORECTAL RESEARCH)[Internet]. 2013;1(3):97-100. Available from: https://sid.ir/paper/334944/en

    IEEE: Copy

    NEDA NAJIBPOUR, MOHAMMAD BAGHER JAHANTAB, MASSOOD HOSSEINZADEH, REZA ROSHANRAVAN, SAM MOSLEMI, SALAR RAHIMI KAZEROONI, ALIREZA SAFARPOUR, LEILA GHAHRAMANI, and SEYED VAHID HOSSEINI, “THE EFFECTS OF HUMAN AMNIOTIC MEMBRANE ON HEALING OF COLONIC ANASTOMOSIS IN DOGS,” IRANIAN JOURNAL OF COLORECTAL RESEARCH (ANNALS OF COLORECTAL RESEARCH), vol. 1, no. 3, pp. 97–100, 2013, [Online]. Available: https://sid.ir/paper/334944/en

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