Massive Blood Transfusions and Outcomes in Trauma Patients; An Intention to Treat Analysis

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Liu Steven; Fujii Quinn; Serio Farris; mcCague Andrew

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Bulletin of Emergency And Trauma Year:2018 | Volume:6 | Issue:3 Page(s): 217-220

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Title

Massive Blood Transfusions and Outcomes in Trauma Patients; An Intention to Treat Analysis

Author(s)

Liu Steven | Fujii Quinn | Serio Farris | mcCague Andrew | Issue Writer Certificate

Keywords

Massive transfusion

Blood transfusion

Trauma

Blood loss

Abstract

Objective: To determine if there exists an upper limit for amount of blood transfused in Trauma patients before it reaches a point of futility. Methods: A prospective cohort study was conducted on 131 patients who received massive Blood transfusion (MBT), defined as 10 U or higher of PRBCs received in the initial 24 hours. Data collected from a Level II Trauma center registry were used to analyze reports of adult patients from July 2014 to 2017. Cohorts were divided by amount of blood received-0 to 9 U, 10-19 U, 20 to 29 U, 30-39 U, 40 U or higher-odds ratio for mortality and p-values for mean Injury Severity Score and overall hospital length of stay were calculated for each group. Results: Odds ratios for massive Blood transfusion groups from 10 units to 39 units each contained the null value, while our 40 units and above group did not (OR 12. 52, 95% CI 1. 3-117. 7). Conclusion: Although this study is limited by its sample size, these results suggests that 40 units of PRBCs may be a threshold at which survival rates begin to decrease significantly.

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APA: Copy

Liu, Steven, Fujii, Quinn, Serio, Farris, & mcCague, Andrew. (2018). Massive Blood Transfusions and Outcomes in Trauma Patients; An Intention to Treat Analysis. BULLETIN OF EMERGENCY AND TRAUMA BEAT, 6(3), 217-220. SID. https://sid.ir/paper/335117/en

Vancouver: Copy

Liu Steven, Fujii Quinn, Serio Farris, mcCague Andrew. Massive Blood Transfusions and Outcomes in Trauma Patients; An Intention to Treat Analysis. BULLETIN OF EMERGENCY AND TRAUMA BEAT[Internet]. 2018;6(3):217-220. Available from: https://sid.ir/paper/335117/en

IEEE: Copy

Steven Liu, Quinn Fujii, Farris Serio, and Andrew mcCague, “Massive Blood Transfusions and Outcomes in Trauma Patients; An Intention to Treat Analysis,” BULLETIN OF EMERGENCY AND TRAUMA BEAT, vol. 6, no. 3, pp. 217–220, 2018, [Online]. Available: https://sid.ir/paper/335117/en

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