The Study on Possible Gene Therapy on Diabetics Type I Using Insulin Gene under Control of Heat Shock Promoter in Laboratory Animals

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Ramezani Keyvan; GHEFLAT SHIVASADAT; JAJARMI VAHID; BANDEHPOUR MOJGAN; KAZEMI BAHRAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: NOVELTY IN BIOMEDICINE Year:2019 | Volume:7 | Issue:2 Page(s): 45-48

Download Full-Text

View:

201

Download:

Cites:

Information Journal Paper

Title

The Study on Possible Gene Therapy on Diabetics Type I Using Insulin Gene under Control of Heat Shock Promoter in Laboratory Animals

Author(s)

Keywords

Diabetes

Gene therapy

Streptozotocin

Abstract

Background: Gene therapy is one of the treatment method for Diabetes mellitus. An insulin gene, under control of heat shock inducer promoter was used in the study. Materials and Methods: Six mice used in this study. Streptozotocin (STZ) induced Diabetes mellitus in BALB/C mice and rats. Recombinant plasmid was injected to each animal. Animal’ s blood sugar (BS) was measured. Warming was done at injection site with a hair dryer to induced gene expression. Results: Immediately after warming blood sugar was increased in mouse 1 and decreased after one hour. However, blood sugar increased again in mice 2 and 4. Blood sugar increased for two hours after warming in mouse 3. Blood sugar increased to 150 mg/dl after STZ injection and immediately after warming reached to 160 mg/dl, after one hour BS dropped to 116 mg/dl and on the second hour was 126 mg/dl, in mouse 5 BS had an increasing trend, BS in mouse 6 had a similar pattern to mouse 2. Conclusion: With fixing the defects of the project will be used in Gene therapy in future.

Cites

No record.

References

No record.

Cite

APA: Copy

Ramezani, Keyvan, GHEFLAT, SHIVASADAT, JAJARMI, VAHID, BANDEHPOUR, MOJGAN, & KAZEMI, BAHRAM. (2019). The Study on Possible Gene Therapy on Diabetics Type I Using Insulin Gene under Control of Heat Shock Promoter in Laboratory Animals. NOVELTY IN BIOMEDICINE, 7(2), 45-48. SID. https://sid.ir/paper/336733/en

Vancouver: Copy

Ramezani Keyvan, GHEFLAT SHIVASADAT, JAJARMI VAHID, BANDEHPOUR MOJGAN, KAZEMI BAHRAM. The Study on Possible Gene Therapy on Diabetics Type I Using Insulin Gene under Control of Heat Shock Promoter in Laboratory Animals. NOVELTY IN BIOMEDICINE[Internet]. 2019;7(2):45-48. Available from: https://sid.ir/paper/336733/en

IEEE: Copy

Keyvan Ramezani, SHIVASADAT GHEFLAT, VAHID JAJARMI, MOJGAN BANDEHPOUR, and BAHRAM KAZEMI, “The Study on Possible Gene Therapy on Diabetics Type I Using Insulin Gene under Control of Heat Shock Promoter in Laboratory Animals,” NOVELTY IN BIOMEDICINE, vol. 7, no. 2, pp. 45–48, 2019, [Online]. Available: https://sid.ir/paper/336733/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops