EFFECT OF ONDANSETRON ON THE INCIDENCE OF KETAMINE ASSOCIATED VOMITING IN PROCEDURAL SEDATION AND ANALGESIA IN CHILDREN: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MAJIDINEJAD SAEED; GOUDARZI LEILA; HEYDARI FARHAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Pediatric Perspectives Year:2018 | Volume:6 | Issue:4 (52) Page(s): 7511-7518

Download Full-Text

View:

246

Download:

150

Cites:

Information Journal Paper

Title

EFFECT OF ONDANSETRON ON THE INCIDENCE OF KETAMINE ASSOCIATED VOMITING IN PROCEDURAL SEDATION AND ANALGESIA IN CHILDREN: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL

Author(s)

MAJIDINEJAD SAEED | GOUDARZI LEILA | HEYDARI FARHAD | Issue Writer Certificate

Keywords

CHILDREN

CONSCIOUS SEDATION

ONDANSETRON

KETAMINE

Abstract

Background Vomiting is a common side effect of KETAMINE in CHILDREN's sedation and there is still controversy about the use of an anti-emetic drug along with KETAMINE to reduce this complication. The aim of this study was to evaluate the effectiveness of ONDANSETRON in controlling vomiting induced by intramuscular (IM), and intravenous (IV) KETAMINE for procedural sedation and analgesia in CHILDREN in the emergency department (ED).Materials and Methods In a double-blind, randomized, placebo-controlled clinical trial, CHILDREN aged 1 to 10 years who received KETAMINE for ED procedures were randomized into four groups receive IV KETAMINE (1.5 mg/kg), and placebo, IM KETAMINE (5mg/kg) and placebo, IV KETAMINE and IV ONDANSETRON (0.15 mg/kg), and IM KETAMINE and oral ONDANSETRON. The incidence of nausea and vomiting and ED length of stay were compared as the outcome of the study.Results One hundred eighty CHILDREN were enrolled and randomized to four groups; 29 patients (15.0%) had nausea and vomiting. The incidence of vomiting was 26.7% in the IV KETAMINE-placebo group and 8.9% in the IV KETAMINE/ IV ONDANSETRON group (P=0.02). The incidence of vomiting was 17.8% in the IM KETAMINE-placebo group and 11.1% in the IM KETAMINE/oral ONDANSETRON group (P=0.17). ED length of stay was similar between groups.Conclusion According to current results, CHILDREN administered IV ONDANSETRON before IV KETAMINE experienced a significantly reduced incidence of vomiting but did not significantly affect length of ED stay and the addition of oral ONDANSETRON to IM KETAMINE dose not reduce vomiting.

Cites

No record.

References

No record.

Cite

APA: Copy

MAJIDINEJAD, SAEED, GOUDARZI, LEILA, & HEYDARI, FARHAD. (2018). EFFECT OF ONDANSETRON ON THE INCIDENCE OF KETAMINE ASSOCIATED VOMITING IN PROCEDURAL SEDATION AND ANALGESIA IN CHILDREN: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL. INTERNATIONAL JOURNAL OF PEDIATRICS, 6(4 (52)), 7511-7518. SID. https://sid.ir/paper/337409/en

Vancouver: Copy

MAJIDINEJAD SAEED, GOUDARZI LEILA, HEYDARI FARHAD. EFFECT OF ONDANSETRON ON THE INCIDENCE OF KETAMINE ASSOCIATED VOMITING IN PROCEDURAL SEDATION AND ANALGESIA IN CHILDREN: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL. INTERNATIONAL JOURNAL OF PEDIATRICS[Internet]. 2018;6(4 (52)):7511-7518. Available from: https://sid.ir/paper/337409/en

IEEE: Copy

SAEED MAJIDINEJAD, LEILA GOUDARZI, and FARHAD HEYDARI, “EFFECT OF ONDANSETRON ON THE INCIDENCE OF KETAMINE ASSOCIATED VOMITING IN PROCEDURAL SEDATION AND ANALGESIA IN CHILDREN: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL,” INTERNATIONAL JOURNAL OF PEDIATRICS, vol. 6, no. 4 (52), pp. 7511–7518, 2018, [Online]. Available: https://sid.ir/paper/337409/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops