PREVALENCE OF ADENOVIRUS AMONG CHILDREN WITH GASTROENTERITIS/ DIARRHEA IN WARRI, DELTA STATE, SOUTHERN, NIGERIA

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QUADRI BOLATITO WILLIAM JOHNSON; OSAZUWA FAVOUR

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Journal: Journal of Pediatric Perspectives Year:2018 | Volume:6 | Issue:5 (53) Page(s): 7651-7652

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Title

PREVALENCE OF ADENOVIRUS AMONG CHILDREN WITH GASTROENTERITIS/ DIARRHEA IN WARRI, DELTA STATE, SOUTHERN, NIGERIA

Author(s)

QUADRI BOLATITO WILLIAM JOHNSON | OSAZUWA FAVOUR | Issue Writer Certificate

Keywords

ADENOVIRUS

CHILDREN

DIARRHEA

NIGERIA

PREVALENCE

Abstract

Dear Editor-in-Chief, ADENOVIRUS are double stranded DNA viruses, known to be capable of causing various kind of illnesses from mild respiratory infections in young CHILDREN (known as thecommon cold) to life-threatening multi-organ disease in people with a weakened immune system (1). In humans, there are 57 accepted human ADENOVIRUS types (HAdV-1 to 57) in seven species (Human ADENOVIRUS A to G) (1). ADENOVIRUS is currently recognized as one of the viral causes of DIARRHEA/gastroenteritis among CHILDREN (2), with types 40 and 41 predominating as common causes of gastroenteritis, especially in CHILDREN under the age of two year-old (2). This letter reports the preliminary investigation on the PREVALENCE of ADENOVIRUS among CHILDREN (under-5 years old) presenting with DIARRHEA/gastroenteritis at the pediatric outpatients of Central Hospital, Warri, a tertiary health care facility in Delta State, South-South, NIGERIA. Ethical approval was provided by the Delta Hospitals Management board in the letter CHW/VOL 1/17/14. This study included a total of 100 subjects, 75 CHILDREN with clinical DIARRHEA/gastroenteritis, and 25 age and sex matched healthy CHILDREN as controls. ADENOVIRUS was detected in fecal specimens of subjects using a rapid lateral flow immunochromatographic assay kit (Gastro Vir-Strip, Coris Bioconcept, Belgium).Data on demographics and social characteristics where obtained with the aid of a self-administered questionnaire. The PREVALENCE of ADENOVIRUS was 14.7% (11/75 patients); ADENOVIRUS was not detected among the control subjects. The PREVALENCE of ADENOVIRUS was more in Males than females, but this were not significantly different (odds ratio [OR]: 0.9592, 95% confidence interval [CI]: 0.2576, 3.5712). ADENOVIRUS PREVALENCE was also independent of age (P=0.9045). The PREVALENCE of ADENOVIRUS in this locality is quite close to the PREVALENCE of 18%, and 19.3% in neighboring states of Ondo and Edo, NIGERIA (3, 4), but less than 23% among CHILDREN in Northwestern, NIGERIA (5). In conclusion, the PREVALENCE of ADENOVIRUS was high; and was independent of age and gender. There is need for routine screening of ADENOVIRUS among CHILDREN with gastroenteritis/diarrhea in our locality irrespective of age or gender. Further studies are needed to provide information on prevalent ADENOVIRUS subtypes and genotypes in this study location.

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APA: Copy

QUADRI BOLATITO, WILLIAM JOHNSON, & OSAZUWA, FAVOUR. (2018). PREVALENCE OF ADENOVIRUS AMONG CHILDREN WITH GASTROENTERITIS/ DIARRHEA IN WARRI, DELTA STATE, SOUTHERN, NIGERIA. INTERNATIONAL JOURNAL OF PEDIATRICS, 6(5 (53)), 7651-7652. SID. https://sid.ir/paper/337431/en

Vancouver: Copy

QUADRI BOLATITO WILLIAM JOHNSON, OSAZUWA FAVOUR. PREVALENCE OF ADENOVIRUS AMONG CHILDREN WITH GASTROENTERITIS/ DIARRHEA IN WARRI, DELTA STATE, SOUTHERN, NIGERIA. INTERNATIONAL JOURNAL OF PEDIATRICS[Internet]. 2018;6(5 (53)):7651-7652. Available from: https://sid.ir/paper/337431/en

IEEE: Copy

WILLIAM JOHNSON QUADRI BOLATITO, and FAVOUR OSAZUWA, “PREVALENCE OF ADENOVIRUS AMONG CHILDREN WITH GASTROENTERITIS/ DIARRHEA IN WARRI, DELTA STATE, SOUTHERN, NIGERIA,” INTERNATIONAL JOURNAL OF PEDIATRICS, vol. 6, no. 5 (53), pp. 7651–7652, 2018, [Online]. Available: https://sid.ir/paper/337431/en

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