Cow’ s Milk Sensitization in Young Children with Gastroesophageal Reflux Disease

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MOGHTADERI MOZHGAN; FARJADIAN SHIRIN; IMANIEH MOHAMMAD HADI; HOSSEINI TESHNIZI SAEED

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Journal Paper

Paper Information

Journal: Journal of Pediatric Perspectives Year:2017 | Volume:5 | Issue:12 (48) Page(s): 6189-6194

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Title

Cow’ s Milk Sensitization in Young Children with Gastroesophageal Reflux Disease

Author(s)

MOGHTADERI MOZHGAN | FARJADIAN SHIRIN | IMANIEH MOHAMMAD HADI | HOSSEINI TESHNIZI SAEED | Issue Writer Certificate

Keywords

Children

Gastroesophageal reflux disease

Patch test

Milk allergy

Skin test

Abstract

Background Recent reports have suggested that Gastroesophageal reflux disease (GERD) is link with cow’ s milk (CM) sensitization in Children. The aim of this study was to determine the frequency of CM sensitization in young Children with GERD. Materials and Methods This cross-sectional study included 33 Children (median age, 2. 93± 1. 90 years) with GERD according to a valid gastroesophageal reflux questionnaire, and 33 healthy Children (median age, 3. 39± 1. 90 years). CMA was diagnosed by Skin test, serum specific immunoglobulin E level and atopy Patch test to milk in both patient and control groups. Results Twenty-four Children with GERD were positive for at least one of the diagnostic tests for CM sensitization compared to 13 Children in control group (odds ratio [OR] = 1. 78; 95% confidence interval [CI]: 1. 14 to 2. 80). Unlike the results of skin prick tests and specific Immunoglobulin E (IgE) levels to milk which showed no difference between Children with GERD and healthy controls, there was a significant difference in the results of Patch test (OR=2. 06; CI95%: 1. 46 to 2. 91). Conclusion Based on our results, CM sensitization is 1. 7 higher in Children with GERD than non-GERD Children. Patch testing preferably would better to perform for diagnosis of CM sensitization in those Children with GERD.

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APA: Copy

MOGHTADERI, MOZHGAN, FARJADIAN, SHIRIN, IMANIEH, MOHAMMAD HADI, & HOSSEINI TESHNIZI, SAEED. (2017). Cow’ s Milk Sensitization in Young Children with Gastroesophageal Reflux Disease. INTERNATIONAL JOURNAL OF PEDIATRICS, 5(12 (48)), 6189-6194. SID. https://sid.ir/paper/337475/en

Vancouver: Copy

MOGHTADERI MOZHGAN, FARJADIAN SHIRIN, IMANIEH MOHAMMAD HADI, HOSSEINI TESHNIZI SAEED. Cow’ s Milk Sensitization in Young Children with Gastroesophageal Reflux Disease. INTERNATIONAL JOURNAL OF PEDIATRICS[Internet]. 2017;5(12 (48)):6189-6194. Available from: https://sid.ir/paper/337475/en

IEEE: Copy

MOZHGAN MOGHTADERI, SHIRIN FARJADIAN, MOHAMMAD HADI IMANIEH, and SAEED HOSSEINI TESHNIZI, “Cow’ s Milk Sensitization in Young Children with Gastroesophageal Reflux Disease,” INTERNATIONAL JOURNAL OF PEDIATRICS, vol. 5, no. 12 (48), pp. 6189–6194, 2017, [Online]. Available: https://sid.ir/paper/337475/en

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