A Comparative Study of Treatment Response of Respiratory Distress Syndrome in Preterm Infants: Early Nasal Intermittent Positive Pressure Ventilation versus Early Nasal Continuous Positive Airway Pressure

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SABZEHEI MOHAMMAD KAZEM; BASIRI BEHNAZ; SHOKOUHI MARYAM; NASER MARYAM

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Journal Paper

Paper Information

Journal: Journal of Pediatric Perspectives Year:2018 | Volume:6 | Issue:10 (58) Page(s): 8339-8346

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Title

A Comparative Study of Treatment Response of Respiratory Distress Syndrome in Preterm Infants: Early Nasal Intermittent Positive Pressure Ventilation versus Early Nasal Continuous Positive Airway Pressure

Author(s)

SABZEHEI MOHAMMAD KAZEM | BASIRI BEHNAZ | SHOKOUHI MARYAM | NASER MARYAM | Issue Writer Certificate

Keywords

Infant

NCPAP

NIPPV

Preterm Infants

Respiratory Distress Syndrome

Abstract

Background Infant Respiratory Distress Syndrome (IRDS) is one of the main causes of serious complications and death in preterm Infants. Both Nasal Continuous Positive Airway Pressure (NCPAP) and Nasal Intermittent Positive Pressure Ventilation (NIPPV) are known as the most common treatment strategies for IRDS. The present study intended to compare NCPAP and NIPPV in the treatment of preterm Infants with Respiratory Distress Syndrome. Materials and Methods To this double blind clinical trial study during a one-year period (2016 to 2017) in Fatemieh Hospital in Hamadan city (Iran), about 60 preterm RDS Infants were randomly assigned into two treatment groups; the NIPPV group received the PIP (14– 20 cmH2O), RR: 30-50/min, PEEP (5– 6 cmH2O), FiO2 up to 60%. The NCPAP group received PEEP (5-6 cmH2o), Flow: 6-7 L/min, and FiO2 up to 60% Results There was not any significant difference in the mean values of gestational age (30. 07± 1. 50 vs. 30. 07± 2. 05; P>0. 05), birth weight (1259± 263 vs. 1235± 285; P>0. 05), and 1-minute Apgar score (5. 53± 1. 13 vs. 5. 33± 1. 34; P>0. 05) between NIPPV and NCPAP treatment groups. Besides, the rate of recovery, mortality and disease complications was not significantly different between both groups. However, the duration of respiratory support was less in NIPPV than NCPAP (34. 9± 33. 8 vs. 68. 4± 32 h; P=0. 001). Conclusion According to the results, there was not significant advantage between the NIPPV vs. NCPAP methods in the treatment of RDS in preterm Infants with very low birth weight.

Cites

The Effect of Surfactant Accompanied by Ventolin on the Respiratory Distress Syndrome in Premature Newborns: A Clinical Trial Study

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APA: Copy

SABZEHEI, MOHAMMAD KAZEM, BASIRI, BEHNAZ, SHOKOUHI, MARYAM, & NASER, MARYAM. (2018). A Comparative Study of Treatment Response of Respiratory Distress Syndrome in Preterm Infants: Early Nasal Intermittent Positive Pressure Ventilation versus Early Nasal Continuous Positive Airway Pressure. INTERNATIONAL JOURNAL OF PEDIATRICS, 6(10 (58)), 8339-8346. SID. https://sid.ir/paper/337612/en

Vancouver: Copy

SABZEHEI MOHAMMAD KAZEM, BASIRI BEHNAZ, SHOKOUHI MARYAM, NASER MARYAM. A Comparative Study of Treatment Response of Respiratory Distress Syndrome in Preterm Infants: Early Nasal Intermittent Positive Pressure Ventilation versus Early Nasal Continuous Positive Airway Pressure. INTERNATIONAL JOURNAL OF PEDIATRICS[Internet]. 2018;6(10 (58)):8339-8346. Available from: https://sid.ir/paper/337612/en

IEEE: Copy

MOHAMMAD KAZEM SABZEHEI, BEHNAZ BASIRI, MARYAM SHOKOUHI, and MARYAM NASER, “A Comparative Study of Treatment Response of Respiratory Distress Syndrome in Preterm Infants: Early Nasal Intermittent Positive Pressure Ventilation versus Early Nasal Continuous Positive Airway Pressure,” INTERNATIONAL JOURNAL OF PEDIATRICS, vol. 6, no. 10 (58), pp. 8339–8346, 2018, [Online]. Available: https://sid.ir/paper/337612/en

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