COMPARISON THE PREVALENCE OF ISOLATED HEPATITIS B CORE ANTIBODY AMONG INJECTION DRUG USERS WITH BLOOD DONORS IN CENTRAL PROVINCE IN IRAN

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SOFIAN M.; MAHDAVIANI F.S.; IZADI N.; MOUSAVINEJAD A.; SARMADIAN H.; ZARINFAR N.; KAHBAZI M.; FARAZI A.A.

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Title

COMPARISON THE PREVALENCE OF ISOLATED HEPATITIS B CORE ANTIBODY AMONG INJECTION DRUG USERS WITH BLOOD DONORS IN CENTRAL PROVINCE IN IRAN

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Keywords

ISOLATED ANTI-HBCQ2

INJECTION DRUG USERSQ3

PREVALENCEQ3

HEPATITISQ3

BLOOD DONORSQ3

Abstract

Background: In healthy BLOOD DONORS, 2%–5% have ISOLATED ANTI-HBC. PREVALENCE of HEPATITIS B, C and co- infection (HBV+HCV) among injection drug user is high. HEPATITIS C suppress of HB SAg and may be HEPATITIS B presented only with isolated anti HBC. This study determined of PREVALENCE of isolated anti HBC among INJECTION DRUG USERS and compare with BLOOD DONORS in Arak city.Methods: A total 684 subjects (531 voluntary BLOOD DONORS and 153 INJECTION DRUG USERS) in Arak, Iran were included in this study. HEPATITIS B surface antigen (HBsAg), HEPATITIS B surface antibody (anti-HBs), anti-HBc, and HEPATITIS C antibody (anti-HCV) were tested in all subjects.Results: A total of 531 voluntary BLOOD DONORS living in the city of Arak, in the Central Province of Iran, with a mean age of 36±10.18 years (range 16-60 years) were enrolled in the study. Ninety-three percent of patients were male and 7% were female. Of the 531 cases, 11 subjects (2.1%) had ISOLATED ANTI-HBC. A total of 153 INJECTION DRUG USERS of Arak, in the Central Province of Iran, with a mean age of 30.66±5.92 years (range 20-50 years) were enrolled in the study. All of them were male. Of the 153 cases, 12 subjects (7.84%) had ISOLATED ANTI-HBC. All of 12 cases were HCV positive.Conclusion: PREVALENCE of ISOLATED ANTI-HBC among INJECTION DRUG USERS was 3. 73 fold in comparison with BLOOD DONORS. For diagnosis of HEPATITIS B in this group test for anti-HBc will be done. Evaluation of occult HEPATITIS B in subject with ISOLATED ANTI-HBC by exact method such as real time PCR is necessary.

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APA: Copy

SOFIAN, M., MAHDAVIANI, F.S., IZADI, N., MOUSAVINEJAD, A., SARMADIAN, H., ZARINFAR, N., KAHBAZI, M., & FARAZI, A.A.. (2011). COMPARISON THE PREVALENCE OF ISOLATED HEPATITIS B CORE ANTIBODY AMONG INJECTION DRUG USERS WITH BLOOD DONORS IN CENTRAL PROVINCE IN IRAN. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 14(3), 173-178. SID. https://sid.ir/paper/33867/en

Vancouver: Copy

SOFIAN M., MAHDAVIANI F.S., IZADI N., MOUSAVINEJAD A., SARMADIAN H., ZARINFAR N., KAHBAZI M., FARAZI A.A.. COMPARISON THE PREVALENCE OF ISOLATED HEPATITIS B CORE ANTIBODY AMONG INJECTION DRUG USERS WITH BLOOD DONORS IN CENTRAL PROVINCE IN IRAN. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2011;14(3):173-178. Available from: https://sid.ir/paper/33867/en

IEEE: Copy

M. SOFIAN, F.S. MAHDAVIANI, N. IZADI, A. MOUSAVINEJAD, H. SARMADIAN, N. ZARINFAR, M. KAHBAZI, and A.A. FARAZI, “COMPARISON THE PREVALENCE OF ISOLATED HEPATITIS B CORE ANTIBODY AMONG INJECTION DRUG USERS WITH BLOOD DONORS IN CENTRAL PROVINCE IN IRAN,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 14, no. 3, pp. 173–178, 2011, [Online]. Available: https://sid.ir/paper/33867/en

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