THE STUDY OF THE EFFECT OF THE EXTRACTBERBERIS VULGARIS ROOT ON SERUM LEVELS OF THYROID HORMONES IN HYPERCHOLESTEROLEMIA RATS

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ZAREI A.; TAHERI S.; CHANGIZI ASHTIYANI S.; REZAEI A.

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Journal: IRANIAN SOUTH MEDICAL JOURNAL (ISMJ) Year:2015 | Volume:18 | Issue:2 Page(s): 270-279

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Title

THE STUDY OF THE EFFECT OF THE EXTRACTBERBERIS VULGARIS ROOT ON SERUM LEVELS OF THYROID HORMONES IN HYPERCHOLESTEROLEMIA RATS

Author(s)

ZAREI A. | TAHERI S. | CHANGIZI ASHTIYANI S. | REZAEI A. | Issue Writer Certificate

Keywords

THYROID HORMONESQ2

BERBERIS VULGARISQ1

CHOLESTEROLQ3

RATQ2

Abstract

Background: The thyroid gland secrete the hormone thyroxin (T4) and triiodothyronine (T3). They have a profound effect on the metabolism of hormones. The aim of this study was to servey the effect of the extract of plant root barberry on the amount of thyroid hormone in RAT having hypercholesterolemia.Materials and Methods: In this experimental study, 40 Wistar RATs were divided into 5 groups (n=8). Control group with normal diet, fat diet group and other groups, the experimental group received the same diet plus fat hydroalcoholic root extract of barberry maximum dose (300), The mean dose of (150), and a minimum dose of (75 mg/kgw) intraperitoneally injection were divided. After the end of this period (21 days), blood sampling and measurement of sample information were analyzed by using the t and Tukey test, and using of SPSS software version 11.5.Results: The results of statistical tests in the receiving groups extract reflects an increased amount of THYROID HORMONES T3 and T4 (P<0.05). The level of TSH in groups receiving the extract did not show significant changes Conclusion: Increases in T3 and T4 levels with no changes in TSH concentration indicate euthyroid hyperthyroxinemia probably.

Cites

THE EFFECT OF ELETTARIA CARDAMOMUM L. FRUIT'S HYDROETHANOLIC EXTRACT ON THYROIDS HORMONES SERUM LEVEL IN HYPOTHYROID MALE MICE

References

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APA: Copy

ZAREI, A., TAHERI, S., CHANGIZI ASHTIYANI, S., & REZAEI, A.. (2015). THE STUDY OF THE EFFECT OF THE EXTRACTBERBERIS VULGARIS ROOT ON SERUM LEVELS OF THYROID HORMONES IN HYPERCHOLESTEROLEMIA RATS. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 18(2), 270-279. SID. https://sid.ir/paper/33931/en

Vancouver: Copy

ZAREI A., TAHERI S., CHANGIZI ASHTIYANI S., REZAEI A.. THE STUDY OF THE EFFECT OF THE EXTRACTBERBERIS VULGARIS ROOT ON SERUM LEVELS OF THYROID HORMONES IN HYPERCHOLESTEROLEMIA RATS. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2015;18(2):270-279. Available from: https://sid.ir/paper/33931/en

IEEE: Copy

A. ZAREI, S. TAHERI, S. CHANGIZI ASHTIYANI, and A. REZAEI, “THE STUDY OF THE EFFECT OF THE EXTRACTBERBERIS VULGARIS ROOT ON SERUM LEVELS OF THYROID HORMONES IN HYPERCHOLESTEROLEMIA RATS,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 18, no. 2, pp. 270–279, 2015, [Online]. Available: https://sid.ir/paper/33931/en

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