مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

163
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

131
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Role of Cytochrome C and Tumor Necrosis Factor-Alpha in Memory Deficit Induced by High Doses of a Commercial Solid Air Freshener in Mice

Pages

  263-274

Abstract

 The study evaluated the role of cytochrome C and Pro-inflammatory cytokines in Memory deficit produced by a commercial solid air freshener (SAF) in male Swiss mice. The animals were culled into 6 groups (n = 7): group 2-6 were exposed to SAF (10, 25, 50, 100 and 200 mg/kg) for 28 consecutive days through whole body exposure. Mice in group 1(control) were exposed to fresh air. Memory function was evaluated on day 28 using standard models. Mice brains were then processed for estimation of tumor necrosis factor-alpha and interleukin-6, Cytochrome C expression and Histomorphologic changes. The chemical constituents of SAF were also determined using GC-MS. SAF (100 and 200 mg/kg) produced memory decline and increased brain contents of tumor necrosis factor-alpha (p <0. 05) but not interleukin-6 (p > 0. 05) relative to control. Increased cytochrome C immunopositive cells, reduced neuronal cells and cytoarchitectural changeswere observed in the hippocampus of mice exposed to SAF (200 g). MS GC-profiling showed the presence of 7 major volatile organic constituents in SAF. Increased release of tumor necrosis factor-alpha and Cytochrome C expression might play a role in SAF-induced Memory deficit in mice.

Multimedia

  • No record.

    • Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    Afighor, Michael, Ajayi, Abayomi M., & UMUKORO, SOLOMON. (2019). Role of Cytochrome C and Tumor Necrosis Factor-Alpha in Memory Deficit Induced by High Doses of a Commercial Solid Air Freshener in Mice. JOURNAL OF CHEMICAL HEALTH RISKS (JCHR), 9(4), 263-274. SID. https://sid.ir/paper/340406/en

    Vancouver: Copy

    Afighor Michael, Ajayi Abayomi M., UMUKORO SOLOMON. Role of Cytochrome C and Tumor Necrosis Factor-Alpha in Memory Deficit Induced by High Doses of a Commercial Solid Air Freshener in Mice. JOURNAL OF CHEMICAL HEALTH RISKS (JCHR)[Internet]. 2019;9(4):263-274. Available from: https://sid.ir/paper/340406/en

    IEEE: Copy

    Michael Afighor, Abayomi M. Ajayi, and SOLOMON UMUKORO, “Role of Cytochrome C and Tumor Necrosis Factor-Alpha in Memory Deficit Induced by High Doses of a Commercial Solid Air Freshener in Mice,” JOURNAL OF CHEMICAL HEALTH RISKS (JCHR), vol. 9, no. 4, pp. 263–274, 2019, [Online]. Available: https://sid.ir/paper/340406/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button