BIOMARKERS, TRAUMA, AND SEPSIS IN PEDIATRICS: A REVIEW

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FRIERI MARIANNE; KUMAR KRISHAN; BOUTIN ANTHONY

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Journal of Pediatrics Review Year:2016 | Volume:4 | Issue:1 Page(s): 0-0

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Information Journal Paper

Title

BIOMARKERS, TRAUMA, AND SEPSIS IN PEDIATRICS: A REVIEW

Author(s)

FRIERI MARIANNE | KUMAR KRISHAN | BOUTIN ANTHONY | Issue Writer Certificate

Keywords

BIOMARKERS

IMMUNITY

TRAUMA

SEPSIS

Abstract

Context: There is a logical connection with BIOMARKERS, TRAUMA, and SEPSIS. This review paper provides new information and clinical practice implications. BIOMARKERS are very important especially in pediatrics. Procalcitonin and other BIOMARKERS are helpful in identifying neonatal SEPSIS, defense mechanisms of the immune system. Pediatric TRAUMA and SEPSIS is very important both in infants and in children. Stress management both in TRAUMA is based upon the notion that stress causes an immune imbalance in susceptible individuals.Evidence Acquisition: Data sources included studies indexed in PubMed, a meta- analysis, predictive values, research strategies, and quality assessments. A recent paper by one of the authors stated marked increase in serum procalcitonin during the course of a septic process often indicates an exacerbation of the illness, and a decreasing level is a sign of improvement. A review of epidemiologic studies on pediatric soccer patients was also addressed. Keywords for searching included BIOMARKERS, IMMUNITY, TRAUMA, and SEPSIS.Results: Of 50 reviewed articles, 34 eligible articles were selected including BIOMARKERS, predictive values for procalcitonin, identifying children at risk for intra-abdominal injuries, blunt TRAUMA, and epidemiology, a meta-analysis. Of neonatal associated SEPSIS, the NF-kappa B pathway by inflammatory stimuli in human neutrophils, predictive value of gelsolin for the outcomes of preterm neonates, a meta-analysis interleukin-8 for neonatal SEPSIS diagnosis.Conclusions: BIOMARKERS are very important especially in pediatrics. Procalcitonin and other BIOMARKERS are helpful in identifying neonatal SEPSIS, defense mechanisms, and physiological functions of the immune system. Pediatric TRAUMA and SEPSIS is very important both in infants and in children. Various topics were covered such as BIOMARKERS, TRAUMA, SEPSIS, inflammation, innate IMMUNITY, role of neutrophils and IL-8, reactive oxygen species, neonatal hypoxia, NF-kappa B related to inflammation.These topics are clearly linked and are very important for pediatricians, pulmonologists, and immunologists in academic centers and in practice.

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APA: Copy

FRIERI, MARIANNE, KUMAR, KRISHAN, & BOUTIN, ANTHONY. (2016). BIOMARKERS, TRAUMA, AND SEPSIS IN PEDIATRICS: A REVIEW. JOURNAL OF PEDIATRICS REVIEW, 4(1), 0-0. SID. https://sid.ir/paper/341184/en

Vancouver: Copy

FRIERI MARIANNE, KUMAR KRISHAN, BOUTIN ANTHONY. BIOMARKERS, TRAUMA, AND SEPSIS IN PEDIATRICS: A REVIEW. JOURNAL OF PEDIATRICS REVIEW[Internet]. 2016;4(1):0-0. Available from: https://sid.ir/paper/341184/en

IEEE: Copy

MARIANNE FRIERI, KRISHAN KUMAR, and ANTHONY BOUTIN, “BIOMARKERS, TRAUMA, AND SEPSIS IN PEDIATRICS: A REVIEW,” JOURNAL OF PEDIATRICS REVIEW, vol. 4, no. 1, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/341184/en

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