ASSOCIATION OF HELICOBACTER PYLORI INFECTION AND ITS CAGA-POSITIVE STRAINS WITH CORONARY HEART DISAESE

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AGHAJANI M.; ABBASIAN M.

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Journal: Iranian South Medical Journal Year:2002 | Volume:5 | Issue:1 Page(s): 56-62

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Title

ASSOCIATION OF HELICOBACTER PYLORI INFECTION AND ITS CAGA-POSITIVE STRAINS WITH CORONARY HEART DISAESE

Author(s)

AGHAJANI M. | ABBASIAN M. | Issue Writer Certificate

Keywords

HELICOBACTER PYLORIQ3

CHD (CORONARY HEART DISEASE)Q2

RISK FACTORSQ3

INFECTIONQ3

Abstract

Introduction: In recent years, involvement of viruses and bacteria in development of atherosclerosis and CHD had been brought in to attention. HELICOBACTER PYLORI is one of these infective agents factors. H.pylori is one of the most common INFECTIONs all over the world. The role of this bacterium and CagA-positive strains in development of some diseases (such as peptic ulcer, gastric cancer,...) has been approved, however, its role in development of cardiovascular disease is under investigation. Methods and Materials: Simple random sampling was done to chose 190 subjects (100 patients with CHD based on coronary angiography in case group and 90 people without CHD in control group who were matched in regard to their age and sex). All the subjects were assessed for demographic characteristics, cardiovascular RISK FACTORS and H.pylori and CagA antibody titers.Results: 70% of patients in case group and 12.2% of people in control group had chronic H. pylori INFECTION (p>0.05). The frequency of coronary RISK FACTORS was similar in H. pylori positive and negative patients. Moreover, 50% of subjects in case group and 56.7% of subjects in control group were infected by CagA+ strains. The prevalance of CagA- strains was %28.6 in case group and %21.5 in control group (p>0,05)Conclusion: We did not find any significant relationship between chronic INFECTION of H. pylori and CagA+ strains and CHD. Probably, it is because of high prevalence of this INFECTION in the society. Moreover, there was no significantly relation between chronic INFECTION of H. pylori and frequency of cardiovascular RISK FACTORS.

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APA: Copy

AGHAJANI, M., & ABBASIAN, M.. (2002). ASSOCIATION OF HELICOBACTER PYLORI INFECTION AND ITS CAGA-POSITIVE STRAINS WITH CORONARY HEART DISAESE. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 5(1), 56-62. SID. https://sid.ir/paper/34120/en

Vancouver: Copy

AGHAJANI M., ABBASIAN M.. ASSOCIATION OF HELICOBACTER PYLORI INFECTION AND ITS CAGA-POSITIVE STRAINS WITH CORONARY HEART DISAESE. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2002;5(1):56-62. Available from: https://sid.ir/paper/34120/en

IEEE: Copy

M. AGHAJANI, and M. ABBASIAN, “ASSOCIATION OF HELICOBACTER PYLORI INFECTION AND ITS CAGA-POSITIVE STRAINS WITH CORONARY HEART DISAESE,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 5, no. 1, pp. 56–62, 2002, [Online]. Available: https://sid.ir/paper/34120/en

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