COMPARISON OF METHODS TO MEASURE GFR IN SOUTH ASIAN POPULATION

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SOHAIB MUHAMMAD

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Journal: Asia Oceania Journal of Nuclear Medicine & Biology Year:2014 | Volume:2 | Issue:SUPPLEMENT 1 Page(s): 27-27

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Title

COMPARISON OF METHODS TO MEASURE GFR IN SOUTH ASIAN POPULATION

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SOHAIB MUHAMMAD | Issue Writer Certificate

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Abstract

Scintigraphic determination of glomerular filtration rate (GFR) using 99mTc‐DTPA is frequently ordered by urologists. Method by Gates is most commonly used despite that its inaccuracies has been reported in several occasions. In this study we compared Gates method (GFRGates) with a Japanese formula by Inoue et al (GFRInoue) in healthy Pakistani population. In phase‐I of the study GFR values by Gates and Inoue methods in 94 healthy potential kidney donors (25 females and 69 males) were compared with Russell’s two plasma sample clearance method (2‐SC). In phase‐I 616 healthy adults were studied for GFR using Gates and Inoue formulae, 24‐our creatinine clearance (GFRCrCl), and Cockcroft‐ault (GFRCG) methods. In phase‐ Inoue’s method had no statistical significant difference (p value 0.22), good correlation (R=0.69) and least bias (‐.91 ml/min/1.73m2, RMSE=11.85 ml/min/1.73m2) with 2‐SC. Gates method on the other hand tended to underestimate GFR by 20.90% with bias of 25.07 ml/min/1.73m2 and RMSE of 29.97. In phase II GFRInoue had better correlation with GFRGates (r=0.67) compared with GFRCrCl (r=0.13) and GFRCG (r=0.08). GFRCrCl and GFRCG had wider scatters (RMSD=21.27 and 21.59 ml/min/1.73m2 respectively) compared with GFRGates (RMSD=14.53 ml/min/1.73m2). All values of GFR tended to underestimate when compared with Inoue's method. Method by Inoue to measure GFR is more accurate in normal South Asian population.

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APA: Copy

SOHAIB, MUHAMMAD. (2014). COMPARISON OF METHODS TO MEASURE GFR IN SOUTH ASIAN POPULATION. ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY, 2(SUPPLEMENT 1), 27-27. SID. https://sid.ir/paper/342032/en

Vancouver: Copy

SOHAIB MUHAMMAD. COMPARISON OF METHODS TO MEASURE GFR IN SOUTH ASIAN POPULATION. ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY[Internet]. 2014;2(SUPPLEMENT 1):27-27. Available from: https://sid.ir/paper/342032/en

IEEE: Copy

MUHAMMAD SOHAIB, “COMPARISON OF METHODS TO MEASURE GFR IN SOUTH ASIAN POPULATION,” ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY, vol. 2, no. SUPPLEMENT 1, pp. 27–27, 2014, [Online]. Available: https://sid.ir/paper/342032/en

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