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Information Journal Paper

Title

Effects of Interleukin Families Polymorphisms on Systemic Lupus Erythematosus: Focus on Interleukin-1 (Review Article)

Pages

  0-0

Abstract

 Systemic Lupus Erythematosus (SLE) is a chronic human autoimmune disease, which is characterized by increased activity of B cells and production of antibodies against tissue antigens. It engages many tissues and organs, including joints, kidneys, heart, and the nervous system. Although the exact pathogenesis of SLE remains to be elucidated, it is suggested that genetic background plays a paramount role in SLE etiology. Increasing evidence is indicating an important role for interleukins in progression of SLE. Interleukins are a group of Cytokines secreted by T helper cells, monocytes, macrophages, and B cells, which are involved in growth and differentiation of T and B cells. The expression level of interleukins is influenced greatly by genetic composition. Therefore, somePolymorphismscan control the expression of interleukins. Consequently, genetic studies can shed lightonour understanding of SLE nature. Therefore, in the present study, the researchers reviewed the roles of eight key interleukin Polymorphisms and their effects on SLE pathogenic.

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    Cite

    APA: Copy

    Moossavi, Maryam, SHOJAEE, MARYAM, Mollashahi, Arezoo, Poodineh, Jafar, MOOSAVI, SEYEDEH ZAHRA, ALAEI, MARYAM, IBRAHIMI, MOSTAFA, & MOHAMMADOO KHORASANI, MILAD. (2018). Effects of Interleukin Families Polymorphisms on Systemic Lupus Erythematosus: Focus on Interleukin-1 (Review Article). GENE, CELL AND TISSUE, 5(1), 0-0. SID. https://sid.ir/paper/345183/en

    Vancouver: Copy

    Moossavi Maryam, SHOJAEE MARYAM, Mollashahi Arezoo, Poodineh Jafar, MOOSAVI SEYEDEH ZAHRA, ALAEI MARYAM, IBRAHIMI MOSTAFA, MOHAMMADOO KHORASANI MILAD. Effects of Interleukin Families Polymorphisms on Systemic Lupus Erythematosus: Focus on Interleukin-1 (Review Article). GENE, CELL AND TISSUE[Internet]. 2018;5(1):0-0. Available from: https://sid.ir/paper/345183/en

    IEEE: Copy

    Maryam Moossavi, MARYAM SHOJAEE, Arezoo Mollashahi, Jafar Poodineh, SEYEDEH ZAHRA MOOSAVI, MARYAM ALAEI, MOSTAFA IBRAHIMI, and MILAD MOHAMMADOO KHORASANI, “Effects of Interleukin Families Polymorphisms on Systemic Lupus Erythematosus: Focus on Interleukin-1 (Review Article),” GENE, CELL AND TISSUE, vol. 5, no. 1, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/345183/en

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