ACUTE/CHRONIC PAIN RELIEF: IS ALTHAEA OFFICINALIS ESSENTIAL OIL EFFECTIVE?

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GOLSHANI YOSEF; ZAREI MOHAMMAD; MOHAMMADI SAEED

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Journal Paper

Paper Information

Journal: Avicenna Journal of Neuropsychophysiology Year:2015 | Volume:2 | Issue:4 Page(s): 0-0

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Title

ACUTE/CHRONIC PAIN RELIEF: IS ALTHAEA OFFICINALIS ESSENTIAL OIL EFFECTIVE?

Author(s)

GOLSHANI YOSEF | ZAREI MOHAMMAD | MOHAMMADI SAEED | Issue Writer Certificate

Keywords

MEDICINAL HERB

PAIN

ESSENTIAL OIL

MOUSE

ALTHAEA OFFICINALIS

Abstract

Background: The Althaea officinal is (marshmallow) plant is traditionally used to treat skin burns and constipation and to reduce inflammation.Objectives: The aim of this study was to evaluate the acute and chronic analgesic effects of the ESSENTIAL OIL of Althaea officinal is leaves (EOAO) in adult male mice.Materials and Methods: This experimental study used thirty-six adult male mice, which were randomly divided into six groups: a control, three groups treated with EOAO (18, 38, or 80 mg/kg, i.p.), a morphine group (1 mg/kg, i.p.), and a group treated with a combination of naloxone (1 mg/kg, i.p.) and 80 mg/kg EOAO. The analgesic effects of EOAO were evaluated by writhing, tail-flick, and formalin tests. The ESSENTIAL OIL of the plant was prepared by the steady distillation method and its composition was analyzed by GC/MS.Results: Significant ant inociceptive effects were noted with doses of 38 and 80 mg/kg EOAO in the chronic phase response of the formalin test (P<0.05 versus control). Doses of 38 and 80 mg/kg EOAO had a significant analgesic effect in the writhing test (P< 0.05 and P<0.01, respectively, versus control). The 80 mg/kg dose of EOAO caused an enhancement in reaction time in the tail-flick test (P<0.01 versus control).Conclusions: EOAO showed an analgesic effect that may involve both the central and peripheral nervous systems.

Cites

ANTINOCICEPTIVE AND ACUTE TOXICITY EFFECTS OF ERIGERON ACER L. IN ADULT MALE RATS

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APA: Copy

GOLSHANI, YOSEF, ZAREI, MOHAMMAD, & MOHAMMADI, SAEED. (2015). ACUTE/CHRONIC PAIN RELIEF: IS ALTHAEA OFFICINALIS ESSENTIAL OIL EFFECTIVE?. AVICENNA JOURNAL OF NEURO PSYCHO PHYSIOLOGY, 2(4), 0-0. SID. https://sid.ir/paper/345253/en

Vancouver: Copy

GOLSHANI YOSEF, ZAREI MOHAMMAD, MOHAMMADI SAEED. ACUTE/CHRONIC PAIN RELIEF: IS ALTHAEA OFFICINALIS ESSENTIAL OIL EFFECTIVE?. AVICENNA JOURNAL OF NEURO PSYCHO PHYSIOLOGY[Internet]. 2015;2(4):0-0. Available from: https://sid.ir/paper/345253/en

IEEE: Copy

YOSEF GOLSHANI, MOHAMMAD ZAREI, and SAEED MOHAMMADI, “ACUTE/CHRONIC PAIN RELIEF: IS ALTHAEA OFFICINALIS ESSENTIAL OIL EFFECTIVE?,” AVICENNA JOURNAL OF NEURO PSYCHO PHYSIOLOGY, vol. 2, no. 4, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/345253/en

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