ASSOCIATION BETWEEN EPSTEIN-BARR VIRUS INFECTION AND B-CELL LYMPHOPROLIFERATIVE DISEASES: A CASE-CONTROL STUDY

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HASHEMI SEYYED HAMID; ABBASI MOHAMMAD; HAJILOOI MEHRDAD; POOROLAJAL JALAL; LAKZADEH LIDA

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Journal: Avicenna Journal of Clinical Microbiology and Infection Year:2015 | Volume:2 | Issue:1 Page(s): 0-0

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Title

ASSOCIATION BETWEEN EPSTEIN-BARR VIRUS INFECTION AND B-CELL LYMPHOPROLIFERATIVE DISEASES: A CASE-CONTROL STUDY

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Keywords

PATIENT

LYMPHOMA

MULTIPLE MYELOMA

Abstract

Background: Epstein-Barr Virus (EBV) is a member of the Herpesviridae family that has infected more than 90% of the worlds’ population. EBV is now considered etiologically associated with the endemic Burkitt's LYMPHOMA, Hodgkin disease, and nasopharyngeal carcinoma. Recent findings show the association between EBV infection and other malignancies.Objectives: The current study aimed to evaluate the relationship between EBV infection and B-cell lymphoproliferative disorders, including LYMPHOMA and MULTIPLE MYELOMA.PATIENTs and Methods: In the current case-control study, a total of 43 PATIENTs with LYMPHOMA and MULTIPLE MYELOMA and 46 age/sex-matched healthy people were included. After taking written consent, serum samples were taken from all subjects. The level of IgG against viral capsid antigen was measured using ELISA. Antibody titers>5 U/mL was considered as positive. Data were analyzed using Stata 11 software.Results: Of the 89 subjects, 53 were male and 36 females, aged 14 to 82 years. There was no significant difference between EBV seroprevalence in the PATIENTs with LYMPHOMA and MULTIPLE MYELOMA, and the healthy subjects.Conclusions: The results of the current study indicated no relationship between latent EBV infection and LYMPHOMA or MULTIPLE MYELOMA. However, further studies with larger sample sizes are required.

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APA: Copy

HASHEMI, SEYYED HAMID, ABBASI, MOHAMMAD, HAJILOOI, MEHRDAD, POOROLAJAL, JALAL, & LAKZADEH, LIDA. (2015). ASSOCIATION BETWEEN EPSTEIN-BARR VIRUS INFECTION AND B-CELL LYMPHOPROLIFERATIVE DISEASES: A CASE-CONTROL STUDY. AVICENNA JOURNAL OF CLINICAL MICROBIOLOGY AND INFECTION, 2(1), 0-0. SID. https://sid.ir/paper/346782/en

Vancouver: Copy

HASHEMI SEYYED HAMID, ABBASI MOHAMMAD, HAJILOOI MEHRDAD, POOROLAJAL JALAL, LAKZADEH LIDA. ASSOCIATION BETWEEN EPSTEIN-BARR VIRUS INFECTION AND B-CELL LYMPHOPROLIFERATIVE DISEASES: A CASE-CONTROL STUDY. AVICENNA JOURNAL OF CLINICAL MICROBIOLOGY AND INFECTION[Internet]. 2015;2(1):0-0. Available from: https://sid.ir/paper/346782/en

IEEE: Copy

SEYYED HAMID HASHEMI, MOHAMMAD ABBASI, MEHRDAD HAJILOOI, JALAL POOROLAJAL, and LIDA LAKZADEH, “ASSOCIATION BETWEEN EPSTEIN-BARR VIRUS INFECTION AND B-CELL LYMPHOPROLIFERATIVE DISEASES: A CASE-CONTROL STUDY,” AVICENNA JOURNAL OF CLINICAL MICROBIOLOGY AND INFECTION, vol. 2, no. 1, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/346782/en

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