ANTIBACTERIAL ACTIVITY OF AZADIRACHTA INDICA LEAF EXTRACTS AGAINST SOME PATHOGENIC STANDARDS AND CLINICAL BACTERIAL ISOLATES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MALEKI LEILA; SADEGHIAN RIZI TAHEREH; GHANNADIAN MOSTAFA; SANATI MOHAMMAD HOSSEIN; SHAFIZADEGAN SHAHIN; SADEGHI ALIABADI HOJJAT

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Avicenna Journal of Clinical Microbiology and Infection Year:2018 | Volume:5 | Issue:1 Page(s): 0-0

Download Full-Text

View:

248

Download:

550

Cites:

Information Journal Paper

Title

ANTIBACTERIAL ACTIVITY OF AZADIRACHTA INDICA LEAF EXTRACTS AGAINST SOME PATHOGENIC STANDARDS AND CLINICAL BACTERIAL ISOLATES

Author(s)

Keywords

MIC

MBC

MIC INDEX

MTT MICRODILUTION METHOD

AZADIRACHTA INDICA

Abstract

Background: AZADIRACHTA INDICA A. Juss (Neem) has been used against a few diseases in traditional medicine. This study was conducted to evaluate the antibacterial activity of Neem leaves extract against some antibiotic sensitive and resistant strains of important human pathogenic bacteria.Methods: The antiMICrobial activities of ethanol, methanol, and ethyl acetate extracts of AZADIRACHTA INDICA A. juss leaves were evaluated against some pathogenic bacterial strains including S. aureus ATCC 6538, E. faecalis ATCC 1394, P. aeroginosa ATCC 9027, E.coli, ATCC 25922, and their clinical isolates using agar well diffusion and MTT MICrodilution methods. MBC was determined by subculturing from MICrodilution assays.Results: The results revealed that methanol extract has the strongest growth inhibitory effect on both standard and clinical isolated strains of P. aeroginosa. Ethyl acetate and ethanol extracts, showing a growth inhibitory effecton both standard and hospital isolated strains ofS. aureus. In the case of E. faecalis, ethanol and methanol extracts showed the highest growth inhibitory effect against standard and clinical strains, respectively. According to the MIC index results, the methanol extract has a bactericidal activity against both standard and nosocomial strains ofS. aureus and P. aeroginosa and bacteriostatic activity against nosocomial strain of E. faecalis.Ethanol extract showed bactericidal activity against both standard and nosocomial strains ofE. faecalis and P. aeroginosa and bacteriostatic activity against nosocomial strain of S. aureus. Ethyl acetate extract had shown bactericidal activity against standard strains ofS. aureus and P. aeroginosa and bacteriostatic against nosocomial strain of S. aureus and standard strain of E. faecalis.Conclusions: Results revealed that Neem may be a prospective therapeutic agent to combat antibiotic resistant bacteria.

Cites

No record.

References

Evaluation of antimicrobial activity of ethanolic extracts of Azadirachta indica and Psidium guajava against clinically important bacteria at varying pH and temperature

Cite

APA: Copy

MALEKI, LEILA, SADEGHIAN RIZI, TAHEREH, GHANNADIAN, MOSTAFA, SANATI, MOHAMMAD HOSSEIN, SHAFIZADEGAN, SHAHIN, & SADEGHI ALIABADI, HOJJAT. (2018). ANTIBACTERIAL ACTIVITY OF AZADIRACHTA INDICA LEAF EXTRACTS AGAINST SOME PATHOGENIC STANDARDS AND CLINICAL BACTERIAL ISOLATES. AVICENNA JOURNAL OF CLINICAL MICROBIOLOGY AND INFECTION, 5(1), 0-0. SID. https://sid.ir/paper/346858/en

Vancouver: Copy

MALEKI LEILA, SADEGHIAN RIZI TAHEREH, GHANNADIAN MOSTAFA, SANATI MOHAMMAD HOSSEIN, SHAFIZADEGAN SHAHIN, SADEGHI ALIABADI HOJJAT. ANTIBACTERIAL ACTIVITY OF AZADIRACHTA INDICA LEAF EXTRACTS AGAINST SOME PATHOGENIC STANDARDS AND CLINICAL BACTERIAL ISOLATES. AVICENNA JOURNAL OF CLINICAL MICROBIOLOGY AND INFECTION[Internet]. 2018;5(1):0-0. Available from: https://sid.ir/paper/346858/en

IEEE: Copy

LEILA MALEKI, TAHEREH SADEGHIAN RIZI, MOSTAFA GHANNADIAN, MOHAMMAD HOSSEIN SANATI, SHAHIN SHAFIZADEGAN, and HOJJAT SADEGHI ALIABADI, “ANTIBACTERIAL ACTIVITY OF AZADIRACHTA INDICA LEAF EXTRACTS AGAINST SOME PATHOGENIC STANDARDS AND CLINICAL BACTERIAL ISOLATES,” AVICENNA JOURNAL OF CLINICAL MICROBIOLOGY AND INFECTION, vol. 5, no. 1, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/346858/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops