EFFICACY MEASUREMENT OF KETOROLAC IN REDUCING THE SEVERITY OF HEADACHE

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BARATLOO ALIREZA; AMIRI MARZIEH; FOROUZANFAR MOHAMMAD MEHDI; HASANI SADEGH; FOUDA SAMAR; NEGIDA AHMED

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Journal: JOURNAL OF EMERGENCY PRACTICE AND TRAUMA Year:2016 | Volume:2 | Issue:1 Page(s): 2-24

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Title

EFFICACY MEASUREMENT OF KETOROLAC IN REDUCING THE SEVERITY OF HEADACHE

Author(s)

Keywords

KETOROLAC

HEADACHE

PAIN MANAGEMENT

EMERGENCY MEDICINE

Abstract

Objective: One of nonsteroidal anti-inflammatory drugs (NSAIDs) named as KETOROLAC is frequently used to relieve acute pain. Current study was conducted with the aim of KETOROLAC efficacy measurement as a pain killer agent for controlling the primary HEADACHE in emergency departments.Methods: In this study, we enrolled 50 patients with primary HEADACHE who received 60 mg KETOROLAC intravenously as a slow infusion in about 10 minutes. Pain scores were evaluated with visual analog scale (VAS) on arrival and also 1 hour and 2 hours after KETOROLAC infusion. Statistical analysis was performed on collected data by using Wilcoxon and Mann-Whitney tests to assess the differences in VAS pain scores.Results: Decreasing the VAS more than 3 points from the arrival until 1 hour (P<0.001), and more than 5 points from the arrival until 2 hours after KETOROLAC administration (P<0.001) were seen. Those with history of analgesic use before admission in emergency department in comparison with the others did not accompany with more decline in pain score after 1 hour (P=0.34) or 2 hours (P=0.92).Conclusion: It seems that KETOROLAC is assured, safe and well tolerated agent for pain control in patients presented with primary HEADACHE to the emergency departments. Based on the results achieved in this study, KETOROLAC illustrates its perceptible effects within 1 hour after administration that even more prominent after 2 hours.

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APA: Copy

BARATLOO, ALIREZA, AMIRI, MARZIEH, FOROUZANFAR, MOHAMMAD MEHDI, HASANI, SADEGH, FOUDA, SAMAR, & NEGIDA, AHMED. (2016). EFFICACY MEASUREMENT OF KETOROLAC IN REDUCING THE SEVERITY OF HEADACHE. JOURNAL OF EMERGENCY PRACTICE AND TRAUMA, 2(1), 2-24. SID. https://sid.ir/paper/347706/en

Vancouver: Copy

BARATLOO ALIREZA, AMIRI MARZIEH, FOROUZANFAR MOHAMMAD MEHDI, HASANI SADEGH, FOUDA SAMAR, NEGIDA AHMED. EFFICACY MEASUREMENT OF KETOROLAC IN REDUCING THE SEVERITY OF HEADACHE. JOURNAL OF EMERGENCY PRACTICE AND TRAUMA[Internet]. 2016;2(1):2-24. Available from: https://sid.ir/paper/347706/en

IEEE: Copy

ALIREZA BARATLOO, MARZIEH AMIRI, MOHAMMAD MEHDI FOROUZANFAR, SADEGH HASANI, SAMAR FOUDA, and AHMED NEGIDA, “EFFICACY MEASUREMENT OF KETOROLAC IN REDUCING THE SEVERITY OF HEADACHE,” JOURNAL OF EMERGENCY PRACTICE AND TRAUMA, vol. 2, no. 1, pp. 2–24, 2016, [Online]. Available: https://sid.ir/paper/347706/en

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