VACUOLATING CYTOTOXIN A (VACA) GENE IN PEPTIC ULCER DISEASE AND NONULCER DYSPEPSIA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FAKHRE YASERI HASHEM; SHAKARABY MEHDI; BRADARAN HAMID REZA; SOLTANI ARABSHHI SEYED KAMRAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF MEDICAL BACTERIOLOGY Year:2016 | Volume:4 | Issue:1-2 Page(s): 47-51

Download Full-Text

View:

291

Download:

Cites:

Information Journal Paper

Title

VACUOLATING CYTOTOXIN A (VACA) GENE IN PEPTIC ULCER DISEASE AND NONULCER DYSPEPSIA

Author(s)

FAKHRE YASERI HASHEM | SHAKARABY MEHDI | BRADARAN HAMID REZA | SOLTANI ARABSHHI SEYED KAMRAN | Issue Writer Certificate

Keywords

PEPTIC ULCER DISEASE

NON-ULCER DYSPEPSIA

VACULATING CYTOTOXIN A (VACA) GENE

VACULATING CYTOTOXIC PROTEIN (VACA)

Abstract

Background: Vaculating cytotoxic A (vacA) gene is one of the multiple Helicobacter pylori genotypes that produce a cytotoxin protein (VacA).This gene is a major cause of chronic peptic ulcers and gastric cancer. The aim of this study was to determine the correlation between vacA gene with PEPTIC ULCER DISEASE (PUD) and NON-ULCER DYSPEPSIA (NUD).Methods: This was a case control study of 130 patients, aged 16-64, with positive H. pylori in histological and Giemsa reports. The case and control groups included 65 PUD patients and 65 NUD patients, respectively. The presence of the vacA gene genotypes was determined using polymerase chain r eaction (PCR) on biopsy samples, taken by endoscopy.Results: In the case group, gastric ulcer was detected in 41.5% (27) of the participants; of whom, 77.8% (21) were female; and duodenal ulcer was found in 58.5% (38) of the participants, of whom, 42.1 % (16) were female. The control group (NUD) included 65 patients; of them, 45% (29) were female and the average age was 36.4±10.8 years (18 to 60).The total frequency of the vacA gene was 53% (69/130), with 60% in the PUD and 46% in the NUD groups (Odds ratio: 1.75, 95% CI: 1.42- 2.12, P=0.25).Conclusion: The vacA gene alone could not be a reliable diagnostic marker for discriminating PEPTIC ULCER DISEASE from NON-ULCER DYSPEPSIA in the Iranian population under study.

Cites

No record.

References

CAGA AND VACA GENOTYPES IN PEPTIC ULCER DISEASE AND NON-ULCER DYSPEPSIA: A CASE-CONTROL STUDY

Cite

APA: Copy

FAKHRE YASERI, HASHEM, SHAKARABY, MEHDI, BRADARAN, HAMID REZA, & SOLTANI ARABSHHI, SEYED KAMRAN. (2016). VACUOLATING CYTOTOXIN A (VACA) GENE IN PEPTIC ULCER DISEASE AND NONULCER DYSPEPSIA. JOURNAL OF MEDICAL BACTERIOLOGY, 4(1-2), 47-51. SID. https://sid.ir/paper/349039/en

Vancouver: Copy

FAKHRE YASERI HASHEM, SHAKARABY MEHDI, BRADARAN HAMID REZA, SOLTANI ARABSHHI SEYED KAMRAN. VACUOLATING CYTOTOXIN A (VACA) GENE IN PEPTIC ULCER DISEASE AND NONULCER DYSPEPSIA. JOURNAL OF MEDICAL BACTERIOLOGY[Internet]. 2016;4(1-2):47-51. Available from: https://sid.ir/paper/349039/en

IEEE: Copy

HASHEM FAKHRE YASERI, MEHDI SHAKARABY, HAMID REZA BRADARAN, and SEYED KAMRAN SOLTANI ARABSHHI, “VACUOLATING CYTOTOXIN A (VACA) GENE IN PEPTIC ULCER DISEASE AND NONULCER DYSPEPSIA,” JOURNAL OF MEDICAL BACTERIOLOGY, vol. 4, no. 1-2, pp. 47–51, 2016, [Online]. Available: https://sid.ir/paper/349039/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops