PREVALENCE AND RISK FACTORS OF HEPATITIS C INFECTION (HCV) IN BIRJAND, IRAN, 2014

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EBRAHIMZADEH AZADEH; AZARKAR ZOHREH; ZIAEE MASOOD; SHARIFZADEH GHOLAMREZA; BIJARI BITA

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Journal: International Journal of Infection Year:2016 | Volume:3 | Issue:1 Page(s): 0-0

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Title

PREVALENCE AND RISK FACTORS OF HEPATITIS C INFECTION (HCV) IN BIRJAND, IRAN, 2014

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Keywords

PREVALENCE

HEPATITIS C (HCV)

RISK FACTORS

Abstract

Background: Hepatitis C virus (HCV) infection is an important global concern, with a frequency of 3% (i.e., 170 million of the population has HCV-Ab). Additionally, 50% of HCV and 80% of transfusion transmitted infections (TTI) are chronic. In 20% of cases, HCV occurs as an acute infection, and in the remaining 80% of cases, it becomes chronic. In chronic patients, risk of cirrhosis is up to 44%, risk of hepatocellular carcinoma (HCC) is 13%, and risk of mortality is 14%. As there is no vaccine available for the virus yet, and since most of the cases are asymptomatic, attention to the epidemiology of the disease among the population is a pressing concern.Objectives: The aim of this study is to determine the PREVALENCE and RISK FACTORS of HCV in Birjand city.Patients and Methods: In this descriptive-analytical study, 5,235 people who live in Birjand city were selected, after gaining permission for the study, a signed consent form was obtained from each patient. PREVALENCE of HCV was determined by ELISA test, and positive cases underwent Polymerase chain reaction (PCR) and genotyping for confirmation.Results: The mean age of the participants was 39.7±14.4. Among them, 52.2% were female and 29.9% had university degrees. PREVALENCE of HCV-Ab+ was about 0.2% with ELISA, and 0.14% of entire group were confirmed by PCR. No significant relationship was found for age, sex, and education (P>0.05). Also, there was no significant relationship found with RISK FACTORS such as endoscopy, blood transfusion, surgery, hospitalization, phlebotomy, and alcohol drinking (P > 0.05). HCV-Ab was 200 times more prevalent in IV-drug abusers compared to non-addicted people. Also, the PREVALENCE of HCV-Ab in non-IV-drug abuser addicts was 9.3 times higher than in non-addict patients. PREVALENCE of HCV-Ab in patients who reported illicit sexual activities was 13.3 times higher. In patients with a familial history of HCV, infection was 26.3 times more prevalent than in patients with no familial history (P<0.001).Conclusions: In this study, the PREVALENCE of HCV was 0.2%, which is lower than the mean PREVALENCE in Iran (1%). PREVALENCE of HCV had a significant relationship with IV-drug abuse.

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APA: Copy

EBRAHIMZADEH, AZADEH, AZARKAR, ZOHREH, ZIAEE, MASOOD, SHARIFZADEH, GHOLAMREZA, & BIJARI, BITA. (2016). PREVALENCE AND RISK FACTORS OF HEPATITIS C INFECTION (HCV) IN BIRJAND, IRAN, 2014. INTERNATIONAL JOURNAL OF INFECTION, 3(1), 0-0. SID. https://sid.ir/paper/349122/en

Vancouver: Copy

EBRAHIMZADEH AZADEH, AZARKAR ZOHREH, ZIAEE MASOOD, SHARIFZADEH GHOLAMREZA, BIJARI BITA. PREVALENCE AND RISK FACTORS OF HEPATITIS C INFECTION (HCV) IN BIRJAND, IRAN, 2014. INTERNATIONAL JOURNAL OF INFECTION[Internet]. 2016;3(1):0-0. Available from: https://sid.ir/paper/349122/en

IEEE: Copy

AZADEH EBRAHIMZADEH, ZOHREH AZARKAR, MASOOD ZIAEE, GHOLAMREZA SHARIFZADEH, and BITA BIJARI, “PREVALENCE AND RISK FACTORS OF HEPATITIS C INFECTION (HCV) IN BIRJAND, IRAN, 2014,” INTERNATIONAL JOURNAL OF INFECTION, vol. 3, no. 1, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/349122/en

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