Effects of Preemptive and Preventive Intravenous Paracetamol on Postoperative Pain and Opioid Consumption in Patients Undergoing Laparoscopic Nephrectomy

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JAFARI ALIREZA; KAMRANMANESH MOHAMMADREZA; AGHAMOHAMMADI HOMAYOUN; GHARAEI BABAK; Noori Khorramabadian Mehranoosh; NAROUIE BEHZAD; Sarmadi Payam; Valipour Reza; VALI ABBAS

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Cellular and Molecular Anesthesia Year:2018 | Volume:3 | Issue:2 Page(s): 74-80

Download Full-Text

View:

153

Download:

103

Cites:

Information Journal Paper

Title

Effects of Preemptive and Preventive Intravenous Paracetamol on Postoperative Pain and Opioid Consumption in Patients Undergoing Laparoscopic Nephrectomy

Author(s)

Keywords

Paracetamol

Preemptive analgesia

Preventive analgesia

PONV

Abstract

Background: Adequate pain control is a goal in postoperative recovery. Although opioids provide good analgesic effects, their side effects such as postoperative nausea and vomiting (PONV) limit their administration. Intravenous Paracetamol as a safe and well-tolerated drug with fewer side effects can be used instead of opioids for pain management. The aim of this study is to compare preemptive or preventive administration of Paracetamol with placebo group to investigate its effects on pain control and opioid consumption in patients undergoing laparoscopic nephrectomy. Materials and Methods: Ninety patients were randomly divided to three groups. Preemptive group received 1 gram Paracetamol in 100 milliliters of 0. 9% saline 30 minutes before induction of anesthesia, the preventive group received 1 gram Paracetamol in 100 milliliters of 0. 9% saline before closure of the skin and placebo group just received 100 milliliters of 0. 9% saline. Post-surgical pain was assessed using verbal rating scale (VRS). Pethidine 0. 25 mg/kg was administered and repeated each 10 minutes to control pain as needed. Pain scores, total dose of opioid and symptoms like nausea and vomiting were recorded. Results: Preemptive and preventive groups had lower pain scores than placebo group. Opioid consumption and PONV were significantly higher in placebo group. No significant differences were observed between Preemptive and preventive groups. Conclusion: Intervenes Paracetamol can provide an adequate pain control with few side effects and may be an effective choice in management of postoperative pain in patients undergoing laparoscopic nephrectomy.

Cites

No record.

References

No record.

Cite

APA: Copy

JAFARI, ALIREZA, KAMRANMANESH, MOHAMMADREZA, AGHAMOHAMMADI, HOMAYOUN, GHARAEI, BABAK, Noori Khorramabadian, Mehranoosh, NAROUIE, BEHZAD, Sarmadi, Payam, Valipour, Reza, & VALI, ABBAS. (2018). Effects of Preemptive and Preventive Intravenous Paracetamol on Postoperative Pain and Opioid Consumption in Patients Undergoing Laparoscopic Nephrectomy. JOURNAL OF CELLULAR AND MOLECULAR ANESTHESIA, 3(2), 74-80. SID. https://sid.ir/paper/350746/en

Vancouver: Copy

JAFARI ALIREZA, KAMRANMANESH MOHAMMADREZA, AGHAMOHAMMADI HOMAYOUN, GHARAEI BABAK, Noori Khorramabadian Mehranoosh, NAROUIE BEHZAD, Sarmadi Payam, Valipour Reza, VALI ABBAS. Effects of Preemptive and Preventive Intravenous Paracetamol on Postoperative Pain and Opioid Consumption in Patients Undergoing Laparoscopic Nephrectomy. JOURNAL OF CELLULAR AND MOLECULAR ANESTHESIA[Internet]. 2018;3(2):74-80. Available from: https://sid.ir/paper/350746/en

IEEE: Copy

ALIREZA JAFARI, MOHAMMADREZA KAMRANMANESH, HOMAYOUN AGHAMOHAMMADI, BABAK GHARAEI, Mehranoosh Noori Khorramabadian, BEHZAD NAROUIE, Payam Sarmadi, Reza Valipour, and ABBAS VALI, “Effects of Preemptive and Preventive Intravenous Paracetamol on Postoperative Pain and Opioid Consumption in Patients Undergoing Laparoscopic Nephrectomy,” JOURNAL OF CELLULAR AND MOLECULAR ANESTHESIA, vol. 3, no. 2, pp. 74–80, 2018, [Online]. Available: https://sid.ir/paper/350746/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops