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Title

PAIN RELIEVING EFFECT OF SUBLINGUAL GLYCEROL TRINITRATE IN RENAL COLIC: A RANDOMIZED PLACEBO-CONTROLLED TRIAL

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  0-0

Abstract

 Introduction: RENAL COLIC is caused by colicky spasms of ureters. As has been shown in previous experiments, glycerol trinitrate (TNG) can inhibit these muscular spasms.Objective: This study was performed to assess the pain relieving effect of TNG among patients referred due to RENAL COLIC pain to the emergency department (ED).Methods: This study is a randomized, placebo-controlled study on 60 patients with RENAL COLIC who were referred to the ED, who were diagnosed clinically to have RENAL COLIC, and their pain was more than 5 based on a visual analogue scale (VAS). The patient's pain was recorded at the moment of clinical diagnosis, and each one received one capsule, either 0.4 mg TNG or placebo, plus a 100 mg indomethacin suppository. The pain score was re-assessed after 5 and 30 min. The values were recorded and compared using SPSS-16 software.Results: Sixty patients with a mean age of 35.75 ± 11.99 years were enrolled (73.3% male). Patients in the two groups were matched for age (p=0.290), sex (p=0.559), and the presence of microscopic hematuria (p=0.292). Pain relief from the start point until the end of the intervention was statistical different in all studied patients (p<0.05); but the comparison between the two groups showed no significant difference in this regard (p=0.440).Conclusion: It is likely that adding TNG to an indomethacin suppository had no significant effects on better PAIN MANAGEMENT of patients referred with RENAL COLIC to the ED.

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APA: Copy

NASEHI, LEYLA, TASLIMI, REZA, DEHPOUR, AHMADREZA, & SEYEDHOSSEINI, JAVAD. (2018). PAIN RELIEVING EFFECT OF SUBLINGUAL GLYCEROL TRINITRATE IN RENAL COLIC: A RANDOMIZED PLACEBO-CONTROLLED TRIAL. (FRONTIERS IN EMERGENCY MEDICINE) ADVANCED JOURNAL OF EMERGENCY MEDICINE, 2(1), 0-0. SID. https://sid.ir/paper/351013/en

Vancouver: Copy

NASEHI LEYLA, TASLIMI REZA, DEHPOUR AHMADREZA, SEYEDHOSSEINI JAVAD. PAIN RELIEVING EFFECT OF SUBLINGUAL GLYCEROL TRINITRATE IN RENAL COLIC: A RANDOMIZED PLACEBO-CONTROLLED TRIAL. (FRONTIERS IN EMERGENCY MEDICINE) ADVANCED JOURNAL OF EMERGENCY MEDICINE[Internet]. 2018;2(1):0-0. Available from: https://sid.ir/paper/351013/en

IEEE: Copy

LEYLA NASEHI, REZA TASLIMI, AHMADREZA DEHPOUR, and JAVAD SEYEDHOSSEINI, “PAIN RELIEVING EFFECT OF SUBLINGUAL GLYCEROL TRINITRATE IN RENAL COLIC: A RANDOMIZED PLACEBO-CONTROLLED TRIAL,” (FRONTIERS IN EMERGENCY MEDICINE) ADVANCED JOURNAL OF EMERGENCY MEDICINE, vol. 2, no. 1, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/351013/en

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