ELECTROCHEMILUMINESENCE EPIDEMIOLOGIC DETECTION OF TOXOPLASMA GONDII INFECTION IN PREGNANT WOMEN WITH DIRECT AND INDIRECT DIAGNOSTIC TECHNIQUES (ELISA AVIDITY PLUS BIOCHEMICAL ASSAY)

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SHARIAT BAHADORY EHSAN; DALIR GHAFFARI ALI; NAMROODI SOMAYEH; MOSAVIPOUR SEYYEDEH SOMAYE; SADRAEI JAVID

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Journal: Epidemiology and Health System Journal Year:2018 | Volume:5 | Issue:1 Page(s): 24-29

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Title

ELECTROCHEMILUMINESENCE EPIDEMIOLOGIC DETECTION OF TOXOPLASMA GONDII INFECTION IN PREGNANT WOMEN WITH DIRECT AND INDIRECT DIAGNOSTIC TECHNIQUES (ELISA AVIDITY PLUS BIOCHEMICAL ASSAY)

Author(s)

Keywords

TOXOPLASMOSIS

BILIRUBIN

ELECTROCHEMILUMINESENCE

FERRITIN

IGG AVIDITY

LIVER FUNCTION

Abstract

Background and aims: TOXOPLASMOSIS is a very common disease in the world. Two types of acquired TOXOPLASMOSIS have been detected. In the chronic TOXOPLASMOSIS, the abnormality of tissue function is little but, in acute TOXOPLASMOSIS, function of RES system becomes interrupted. The assessment of toxoplasma antibody with tissue enzymes in this stage is very important. Furthermore, serum FERRITIN in some conditions became high in acute phase of infectious disease.Methods: This study was based on comparative abundance study. Materials consisted of 980 serum and amniotic fluid samples collected from human blood with high level of IgG antibody against Toxoplasma gondii in Rajaie center, Tehran, Iran. The standard test was ELISA assay to detect these antibodies and the main test was measurement of liver transaminases (SGOT, SGPT) BILIRUBIN and FERRITIN to evaluate acute TOXOPLASMOSIS. Data analysis was done by SPSS version 18.0. This study was done during March to June, 2017.Results: Results showed that in some patients with high level of IGG AVIDITY antibody against T. gondii the level of liver transaminases, serum BILIRUBIN and FERRITIN became increased. For example in 120 patients with acute TOXOPLASMOSIS the mean serum levels of SGOT were 108 IU/L and in 80 patients the mean serum BILIRUBIN were about 5 mg/dL.Conclusion: In acute congenital TOXOPLASMOSIS, the evaluation of IGG AVIDITY was first step and then the measurement of biochemical factors such as serum transaminases, serum BILIRUBIN and serum FERRITIN were important.

Cites

Molecular Identification of Toxoplasma gondii in the Native Slaughtered Cattle of Tehran Province, Iran

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APA: Copy

SHARIAT BAHADORY, EHSAN, DALIR GHAFFARI, ALI, NAMROODI, SOMAYEH, MOSAVIPOUR, SEYYEDEH SOMAYE, & SADRAEI, JAVID. (2018). ELECTROCHEMILUMINESENCE EPIDEMIOLOGIC DETECTION OF TOXOPLASMA GONDII INFECTION IN PREGNANT WOMEN WITH DIRECT AND INDIRECT DIAGNOSTIC TECHNIQUES (ELISA AVIDITY PLUS BIOCHEMICAL ASSAY). EPIDEMIOLOGY AND HEALTH SYSTEM JOURNAL (INTERNATIONAL JOURNAL OF EPIDEMIOLOGIC RESEARCH), 5(1), 24-29. SID. https://sid.ir/paper/351423/en

Vancouver: Copy

SHARIAT BAHADORY EHSAN, DALIR GHAFFARI ALI, NAMROODI SOMAYEH, MOSAVIPOUR SEYYEDEH SOMAYE, SADRAEI JAVID. ELECTROCHEMILUMINESENCE EPIDEMIOLOGIC DETECTION OF TOXOPLASMA GONDII INFECTION IN PREGNANT WOMEN WITH DIRECT AND INDIRECT DIAGNOSTIC TECHNIQUES (ELISA AVIDITY PLUS BIOCHEMICAL ASSAY). EPIDEMIOLOGY AND HEALTH SYSTEM JOURNAL (INTERNATIONAL JOURNAL OF EPIDEMIOLOGIC RESEARCH)[Internet]. 2018;5(1):24-29. Available from: https://sid.ir/paper/351423/en

IEEE: Copy

EHSAN SHARIAT BAHADORY, ALI DALIR GHAFFARI, SOMAYEH NAMROODI, SEYYEDEH SOMAYE MOSAVIPOUR, and JAVID SADRAEI, “ELECTROCHEMILUMINESENCE EPIDEMIOLOGIC DETECTION OF TOXOPLASMA GONDII INFECTION IN PREGNANT WOMEN WITH DIRECT AND INDIRECT DIAGNOSTIC TECHNIQUES (ELISA AVIDITY PLUS BIOCHEMICAL ASSAY),” EPIDEMIOLOGY AND HEALTH SYSTEM JOURNAL (INTERNATIONAL JOURNAL OF EPIDEMIOLOGIC RESEARCH), vol. 5, no. 1, pp. 24–29, 2018, [Online]. Available: https://sid.ir/paper/351423/en

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