مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Differentiation of Periodontal Ligament Stem Cells Into Osteoblasts on Hybrid Alginate/ Polyvinyl Alcohol/ Hydroxyapatite Nanofibrous Scaffolds

Pages

  0-0

Abstract

 The efficacy of Alginate/ Polyvinyl Alcohol/ Hydroxyapatite nanopowders (Alg/PVA/HANPs) mats was investigated for increasing Periodontal Ligament Stem Cells (PDLSCs) differentiation into the Osteoblast Cells. The Alg/PVA/HANPs nanofibers were fabricated through electospinning process and following ionic crosslinking of Ca+2 and glutaraldehyde crosslinkers. The physical features of mats and expression of osteoblast cell markers were evaluated. Results showed the diameter of nanofiber increases with decreasing the incorporation of HANPs in Alg/PVA nanofiber. According to MTT assay the viability of cells on scaffolds are better in the all of groups, so the scaffolds were not toxic for the cultured cells. The osteogenic culture media appropriately enhanced osteopontin and osteocalcin markers. Furthermore, in vitro study indicated that the Alg/PVA/HANPs nanofiber provided a suitable three-dimensional structure for Osteoblast Cells differentiation. Thus, the Alg/PVA/HANPs scaffold can be recommended for in bone repair.

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    Cite

    APA: Copy

    BAHRAMI, NAGHMEH, BAYAT, MOHAMMAD, Ai, Armin, Khanmohammadi, Mehdi, AI, JAFAR, AHMADI, AKBAR, SALEHI, MAJID, EBRAHIMI BAROUGH, SOMAYEH, GOODARZI, ARASH, KARIMI, ROYA, MOHAMADNIA, ABDOLREZA, & RAHIMI, AZAM. (2018). Differentiation of Periodontal Ligament Stem Cells Into Osteoblasts on Hybrid Alginate/ Polyvinyl Alcohol/ Hydroxyapatite Nanofibrous Scaffolds. ARCHIVES OF NEUROSCIENCE, 5(4), 0-0. SID. https://sid.ir/paper/354678/en

    Vancouver: Copy

    BAHRAMI NAGHMEH, BAYAT MOHAMMAD, Ai Armin, Khanmohammadi Mehdi, AI JAFAR, AHMADI AKBAR, SALEHI MAJID, EBRAHIMI BAROUGH SOMAYEH, GOODARZI ARASH, KARIMI ROYA, MOHAMADNIA ABDOLREZA, RAHIMI AZAM. Differentiation of Periodontal Ligament Stem Cells Into Osteoblasts on Hybrid Alginate/ Polyvinyl Alcohol/ Hydroxyapatite Nanofibrous Scaffolds. ARCHIVES OF NEUROSCIENCE[Internet]. 2018;5(4):0-0. Available from: https://sid.ir/paper/354678/en

    IEEE: Copy

    NAGHMEH BAHRAMI, MOHAMMAD BAYAT, Armin Ai, Mehdi Khanmohammadi, JAFAR AI, AKBAR AHMADI, MAJID SALEHI, SOMAYEH EBRAHIMI BAROUGH, ARASH GOODARZI, ROYA KARIMI, ABDOLREZA MOHAMADNIA, and AZAM RAHIMI, “Differentiation of Periodontal Ligament Stem Cells Into Osteoblasts on Hybrid Alginate/ Polyvinyl Alcohol/ Hydroxyapatite Nanofibrous Scaffolds,” ARCHIVES OF NEUROSCIENCE, vol. 5, no. 4, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/354678/en

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