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Title

Can computerized tomography Hounsfield unit values be useful in the differential diagnosis of pleural effusion?

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Abstract

 Introduction: We aimed to investigate the efficacy of Hounsfield unit (HU) Attenuation measured on Computed tomography (CT) as a non-invasive method for Pleural effusion characterization. Methods: Patients with Pleural effusion who underwent thoracic CT imaging and thoracentesis within a maximum of three days were included in this retrospective study (15 transudate and 36 exudate). By drawing a circular region of interest (ROI) on the section with the thickest Pleural effusion in terms of anteroposterior diameter in the upper-medial-lower zone on axial images, a total of three HU values, one from each level, were averaged. An independent t-test was applied to the CT Attenuation (HU) values for the transudate-exudate differentiation. A receiver operating characteristic (ROC) analysis was then made. Results: The mean Attenuation ± standard deviation (minimum-maximum) value for the patients with transudate was 2. 17 ± 3. 76 ((-7. 5)-7. 5) HU, whereas the mean HU value for the patients with exudate was 8. 38 ± 6. 2 ((-6)-22). The independent t test made for the transudate-exudate differentiation revealed a statistically significant difference (P = 0. 001). In the ROC analysis carried out to determine the cut-off value of the Attenuation value of Pleural effusion in the transudate-exudate differentiation, the area under the curve was found to be 82. 8%. When the cut-off value was taken as 2. 75HU for the area under the curve, sensitivity was found to be 84%, and specificity was 60%. Conclusion: Although CT-HU values are statistically significant in the differential diagnosis of transudate-exudate, there is still a need to establish a correlation with other tomographic findings and clinical laboratory findings.

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    APA: Copy

    Durmaz, Fatma, OZGOKCE, MESUT, Ayyildiz, Veysel Atilla, Cilingir, Buket Mermit, & GOYA, CEMIL. (2020). Can computerized tomography Hounsfield unit values be useful in the differential diagnosis of pleural effusion?. JOURNAL OF RESEARCH IN CLINICAL MEDICINE, 8(1), 0-0. SID. https://sid.ir/paper/355195/en

    Vancouver: Copy

    Durmaz Fatma, OZGOKCE MESUT, Ayyildiz Veysel Atilla, Cilingir Buket Mermit, GOYA CEMIL. Can computerized tomography Hounsfield unit values be useful in the differential diagnosis of pleural effusion?. JOURNAL OF RESEARCH IN CLINICAL MEDICINE[Internet]. 2020;8(1):0-0. Available from: https://sid.ir/paper/355195/en

    IEEE: Copy

    Fatma Durmaz, MESUT OZGOKCE, Veysel Atilla Ayyildiz, Buket Mermit Cilingir, and CEMIL GOYA, “Can computerized tomography Hounsfield unit values be useful in the differential diagnosis of pleural effusion?,” JOURNAL OF RESEARCH IN CLINICAL MEDICINE, vol. 8, no. 1, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/355195/en

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