Association of the ability to taste Phenylthiocarbamide with sex and smoking

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Iranmanesh Mohammad; MASOUDI RAHELEH; Gholami Shakiba

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2018 | Volume:26 | Issue:7 Page(s): 615-623

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Information Journal Paper

Title

Association of the ability to taste Phenylthiocarbamide with sex and smoking

Author(s)

Iranmanesh Mohammad | MASOUDI RAHELEH | Gholami Shakiba | Issue Writer Certificate

Keywords

PhenylthiocarbamideQ1

TasterQ2

Non-tasterQ1

SexQ2

SmokingQ3

Abstract

Introdution: The ability to taste Phenylthiocarbamide (PTC) has been long studied from genetics, epidemiologic and evolutionary point of view. Variation in the frequency of Tasters and non-Tasters could reflect the food preferences. Moreover, it can be a marker for diet-related diseases. The frequency of PTC taste sensitivity has been studied in many populations. The aim of this research was to determine the frequency of Tasters and not-Tasters in a population from Iran and the association of Sex and Smoking with the ability to taste PTC. Methods: In a random cross sectional study, 175 individuals from Shiraz University or their families were examined regarding the ability to taste PTC after filling out a questionnaire and tasting PTC. The statistical analysis was carried out using SPSS, version 21, applying the Chi square, logistic regression, confidence interval (CI), and odd ratio (OR). Results: The frequency of T, and t alleles was 0. 58 and 0. 42, respectively. There was 82. 23% Taster versus 17. 77% non-Taster. There was a significant difference (p=0. 007, OR=4. 044) between male and female regarding the ability of tasting PTC. There was more non-Taster among smokers compared to non-smokers (p= 0. 002, OR=0. 278). Conclusion: To the best of the authors’ knowledge, this is the first study to investigate the frequency of PTC Tasters in Iran. Similar to the studies from other populations, the frequency of PTC Tasters was higher compared to non-Tasters in our population. Moreover, there were more Tasters in females than male individuals. In addition, frequency of Tasters was more in no-smokers compared to smokers. Investigating the connections between taste perception and Smoking may help to find a reliable indicator for Smoking susceptibility. However, larger sample size and genetic tests are necessary to draw a comprehensive conclusion.

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References

Genetic variation in bitter taste receptor gene TAS2R38, PROP taster status and their association with body mass index and food preferences in Indian population

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APA: Copy

Iranmanesh, Mohammad, MASOUDI, RAHELEH, & Gholami, Shakiba. (2018). Association of the ability to taste Phenylthiocarbamide with sex and smoking. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 26(7 ), 615-623. SID. https://sid.ir/paper/35701/en

Vancouver: Copy

Iranmanesh Mohammad, MASOUDI RAHELEH, Gholami Shakiba. Association of the ability to taste Phenylthiocarbamide with sex and smoking. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;26(7 ):615-623. Available from: https://sid.ir/paper/35701/en

IEEE: Copy

Mohammad Iranmanesh, RAHELEH MASOUDI, and Shakiba Gholami, “Association of the ability to taste Phenylthiocarbamide with sex and smoking,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 7 , pp. 615–623, 2018, [Online]. Available: https://sid.ir/paper/35701/en

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