Production of bacterial cellulose scaffold contains herb extract and assessment of its healing effects in rat cutaneous wounds

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Ebrahimian Mobina; Yahyaei Behrooz; MANAFI SAHEBALI

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2018 | Volume:26 | Issue:9 Page(s): 820-831

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Title

Production of bacterial cellulose scaffold contains herb extract and assessment of its healing effects in rat cutaneous wounds

Author(s)

Ebrahimian Mobina | Yahyaei Behrooz | MANAFI SAHEBALI | Issue Writer Certificate

Keywords

CelluloseQ1

Wound healingQ2

Gluconacetobacter xylinusQ1

Zingiber officinaleQ1

Abstract

Introdution: Natural Cellulose is a normal Wound healing remedy that can improve the Wound healing properties by combining with some herbal extracts. The aim of this study was to evaluate the production of bacterial Cellulose containing Zingiber extract and to evaluate its healing effects in rat cutaneous wounds. Methods: In this experimental study, Gluconacetobacter xylinus was first cultured in a hysterine-scrum culture medium under static conditions and aqueous extract of Zingiber officinale plant was prepared. Then, Microculture Tetrazolium Test (MTT) was performed to evaluate the cytotoxicity of the aqueous extract of Zingiber officinale, and finally the healing process was investigated on rat cutaneous ulcers in different days of treatment. Results: The results of this study have shown that the Cellulose layer was manufactured, tight, non-fracture and with pH = 7/005, which had the proper repair wound of 80%. The extract of the Zingiber officinale plant in the MTT test had toxicity to the cells, which has the same toxicity for cancerous and non-cancerous cells. For Wound healing, the non-toxic concentration of the extract was used, and the results of the Wound healing showed that Cellulose and Zingiber officinale extract can be used as a suitable drug for Wound healing. Conclusion: Gluconacetobacter xylinus is effective in healing and wound, also the Zingiber officinale plant has a miraculous effect on open wounds.

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APA: Copy

Ebrahimian, Mobina, Yahyaei, Behrooz, & MANAFI, SAHEBALI. (2018). Production of bacterial cellulose scaffold contains herb extract and assessment of its healing effects in rat cutaneous wounds. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 26(9 ), 820-831. SID. https://sid.ir/paper/35722/en

Vancouver: Copy

Ebrahimian Mobina, Yahyaei Behrooz, MANAFI SAHEBALI. Production of bacterial cellulose scaffold contains herb extract and assessment of its healing effects in rat cutaneous wounds. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;26(9 ):820-831. Available from: https://sid.ir/paper/35722/en

IEEE: Copy

Mobina Ebrahimian, Behrooz Yahyaei, and SAHEBALI MANAFI, “Production of bacterial cellulose scaffold contains herb extract and assessment of its healing effects in rat cutaneous wounds,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 9 , pp. 820–831, 2018, [Online]. Available: https://sid.ir/paper/35722/en

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