CASE REPORT: MULTIPLE MYELOMA WITH GANGRENE OF EXTREMITIES

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MORTAZAVIZADEH M.R.; KARIMI MAHMOUD; AKHAVAN TAFTI M.; SOLEYMANI SALEHABADI H.; OULIA M.B.; GHARAHI N.

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2009 | Volume:17 | Issue:3 (66) Page(s): 193-196

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Title

CASE REPORT: MULTIPLE MYELOMA WITH GANGRENE OF EXTREMITIES

Author(s)

Keywords

MULTIPLE MYELOMAQ3

CRYOGLOBULINEMIAQ3

GANGRENEQ3

Abstract

Introduction: MULTIPLE MYELOMA represents a malignant proliferation of plasma cells derived from a single clone and it results in bone pain or fracture, renal failure, susceptibility to infections, anemia and hypercalcemia. The hyper viscosity syndrome is rare. Cryoglobulins are immunoglubulins that precipitate at temperatures less than 37degrees Celsius. Monoclonal cryoglobulins are usually present along with a specific hematologic disorder and are often asymptomatic. We report a second case of MULTIPLE MYELOMA with GANGRENE of all four extremities.Case: The Patient was a 77 year–old farmer with a 2 weeks history of coldness, pain and discoloration of the fingers of both the extremities which had extended to the mid forearm and shin regions. It was accompanied by skin erosions of the lower extremities, dark spots on the ear auricles and discoloration of the tip of the nose. On physical examination, quadrigangrene associated with ischemia of the auricles and tip of nose was seen. Serum proteins electrophoresis demonstrated monoclonal gammopathy and serum was positive for cryoglobulin, Bone marrow study showed neoplastic plasma cells infiltration. The patient was diagnosed as CRYOGLOBULINEMIA based on MULTIPLE MYELOMA and treated accordingly.

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APA: Copy

MORTAZAVIZADEH, M.R., KARIMI, MAHMOUD, AKHAVAN TAFTI, M., SOLEYMANI SALEHABADI, H., OULIA, M.B., & GHARAHI, N.. (2009). CASE REPORT: MULTIPLE MYELOMA WITH GANGRENE OF EXTREMITIES. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 17(3 (66)), 193-196. SID. https://sid.ir/paper/35746/en

Vancouver: Copy

MORTAZAVIZADEH M.R., KARIMI MAHMOUD, AKHAVAN TAFTI M., SOLEYMANI SALEHABADI H., OULIA M.B., GHARAHI N.. CASE REPORT: MULTIPLE MYELOMA WITH GANGRENE OF EXTREMITIES. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;17(3 (66)):193-196. Available from: https://sid.ir/paper/35746/en

IEEE: Copy

M.R. MORTAZAVIZADEH, MAHMOUD KARIMI, M. AKHAVAN TAFTI, H. SOLEYMANI SALEHABADI, M.B. OULIA, and N. GHARAHI, “CASE REPORT: MULTIPLE MYELOMA WITH GANGRENE OF EXTREMITIES,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 3 (66), pp. 193–196, 2009, [Online]. Available: https://sid.ir/paper/35746/en

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