LIPOPROTEIN (Α) IN PATIENTS WITH VARIOUS HYPERLIPIDAEMIA

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JALALI B.A.; MOZAFARI H.; AMOUZGAR F.; NEMATKHAH A.; PARSAEIAN N.

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2000 | Volume:8 | Issue:2 Page(s): 93-97

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Title

LIPOPROTEIN (Α) IN PATIENTS WITH VARIOUS HYPERLIPIDAEMIA

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Keywords

LIPOPROTEIN (A)Q3

HYPERLIPIDEAMIAQ3

CORONARY ARTERY DISEASEQ3

Abstract

Lipoprotein (a) [Lp (a)], a cholesterol -rich plasma lipoprotein which is structurally similar to low density lipoprotein (LDL), is an independent risk factor for CORONARY ARTERY DISEASE. In addition to genetic background, some other factors such as hyperlipidaemia may influence plasma Lp (a) levels. In the present study, the Lp (a) levels in various hyperlipidaemic patients are evaluated in full. Study populations (110 females, 170 males) were selected from subjects referred to clinical laboratory for lipid analysis. Lipids and lipoproteins were measured by routine methods and Lp (a) assay was done by electroimmunodifusion. Lp (a) levels in hypercholesterolemic (Mean = 41 mg / dl ) and mixed hyperlipidaemia ( Mean =43 mg /dl ) groups were significantly higher than control group ( 23 mg / dl ). No differences were found between hypertriglyceridaemic patients ( Mean =24 mg /dl ) and controls. Furthermore, a positive correlation was found between Lp (a) and cholesterol (r = 0.25, P < 0.001) in hyperlipidaemic patients, but no correlation was observed with triglyceride. In conclusion, plasma Lp (a) concentrations are elevated in hyperlipidaemia if the patients have high cholesterol levels. However, it is normal or even low in hypertriglyceridaemic cases.

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APA: Copy

JALALI, B.A., MOZAFARI, H., AMOUZGAR, F., NEMATKHAH, A., & PARSAEIAN, N.. (2000). LIPOPROTEIN (Α) IN PATIENTS WITH VARIOUS HYPERLIPIDAEMIA. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 8(2), 93-97. SID. https://sid.ir/paper/35767/en

Vancouver: Copy

JALALI B.A., MOZAFARI H., AMOUZGAR F., NEMATKHAH A., PARSAEIAN N.. LIPOPROTEIN (Α) IN PATIENTS WITH VARIOUS HYPERLIPIDAEMIA. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2000;8(2):93-97. Available from: https://sid.ir/paper/35767/en

IEEE: Copy

B.A. JALALI, H. MOZAFARI, F. AMOUZGAR, A. NEMATKHAH, and N. PARSAEIAN, “LIPOPROTEIN (Α) IN PATIENTS WITH VARIOUS HYPERLIPIDAEMIA,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 8, no. 2, pp. 93–97, 2000, [Online]. Available: https://sid.ir/paper/35767/en

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