مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

594
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Investigating the expression of Beclin1 and LC3 genes in patients with non-small cell lung cancer

Pages

  112-122

Abstract

 Aim: In the present study, the expression of Beclin1 and LC3 genes has been investigated in 30 patients with non-small cell lung cancer. Material and methods: RNA was extracted from tumor and adjacent normal tissues of 30 patients with non-small cell lung cancer. After synthesis of cDNA, real time-PCR was exploited for quantitative expression of Beclin1 and LC3 genes. Also, the expression of these genes was compared with the clinical and pathological findings of the patients. Results: the expression levels of Beclin1 (P<0. 0001) and LC3 (p<0. 0001) genes increased significantly. Also, there was a significant correlation between increasing the expression of LC3 with the subtype of tissue (P=0. 01). Conclusion: The increased expression of Beclin-1 and LC3 genes may enhance the process of autophagy and this condition can develop tumorigenesis; however more research is needed to confirm these findings.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    Akbari Kelishomi, M., ZARE KARIZI, SH., & KARIMIPOOR, M.. (2018). Investigating the expression of Beclin1 and LC3 genes in patients with non-small cell lung cancer. JOURNAL OF CELL & TISSUE, 9(2 ), 112-122. SID. https://sid.ir/paper/360287/en

    Vancouver: Copy

    Akbari Kelishomi M., ZARE KARIZI SH., KARIMIPOOR M.. Investigating the expression of Beclin1 and LC3 genes in patients with non-small cell lung cancer. JOURNAL OF CELL & TISSUE[Internet]. 2018;9(2 ):112-122. Available from: https://sid.ir/paper/360287/en

    IEEE: Copy

    M. Akbari Kelishomi, SH. ZARE KARIZI, and M. KARIMIPOOR, “Investigating the expression of Beclin1 and LC3 genes in patients with non-small cell lung cancer,” JOURNAL OF CELL & TISSUE, vol. 9, no. 2 , pp. 112–122, 2018, [Online]. Available: https://sid.ir/paper/360287/en

    Related Journal Papers

    Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops





    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button