Evaluation of Ovarian Reserve after Laparoscopic Cystectomy for Endometrioma with or without Vasopressin Injection: A Randomized Clinical Trial Study

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ROUHOLAMIN SAFOURA; Ahmadpour Ghazvini Farzaneh

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Journal: Journal of Isfahan Medical School Year:2019 | Volume:37 | Issue:514 Page(s): 48-54

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Information Journal Paper

Title

Evaluation of Ovarian Reserve after Laparoscopic Cystectomy for Endometrioma with or without Vasopressin Injection: A Randomized Clinical Trial Study

Author(s)

ROUHOLAMIN SAFOURA | Ahmadpour Ghazvini Farzaneh | Issue Writer Certificate

Keywords

EndometriumQ1

Ovarian reserveQ1

VasopressinsQ3

Abstract

Background: Laparoscopic cystectomy for ovarian endometrioma, despite its high usefulness, reduces Ovarian reserve; so, several methods are proposed to reduce this problem. This study was designed to evaluate the effect of vasopressin injection in laparoscopic cystectomy on Ovarian reserve in patients with unilateral endometrioma. Methods: In this clinical trial study, 66 women with unilateral endometrioma undergoing laparoscopic cystectomy were divided into two groups of 33. The first group received vasopressin via injection, and the second group did not received any drug via injection. Anti-Muller hormone (AMH) level before and 6 months after surgery as well as hemoglobin level before and 6 hours after surgery were measured and compared. Findings: The mean AMH level before and after the intervention was 3. 43 ± 2. 46 and 2. 67 ± 1. 5 ng/ml (P = 0. 070), and 3. 49 ± 2. 48 and 1. 61 ± 1. 79 ng/ml (P = 0. 040) in intervention and control groups, respectively. The level of AMH reduction in vasopressin injection group was lower than control group. The mean hemoglobin level before and after treatment was 11. 97 ± 1. 12 and 11. 29 ± 0. 97 (P = 0. 69) and 11. 5 ± 1. 79 and 10. 23± 1. 99 g/dl (P < 0. 001) in intervention and control groups, respectively, and blood loss in vasopressin injection group was lower than control group. Conclusion: It seems that vasopressin injection reduce blood-loss, ovarian damage, and the damage to Ovarian reserve during laparoscopic cystectomy for ovarian endometrioma.

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APA: Copy

ROUHOLAMIN, SAFOURA, & Ahmadpour Ghazvini, Farzaneh. (2019). Evaluation of Ovarian Reserve after Laparoscopic Cystectomy for Endometrioma with or without Vasopressin Injection: A Randomized Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 37(514 ), 48-54. SID. https://sid.ir/paper/361906/en

Vancouver: Copy

ROUHOLAMIN SAFOURA, Ahmadpour Ghazvini Farzaneh. Evaluation of Ovarian Reserve after Laparoscopic Cystectomy for Endometrioma with or without Vasopressin Injection: A Randomized Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2019;37(514 ):48-54. Available from: https://sid.ir/paper/361906/en

IEEE: Copy

SAFOURA ROUHOLAMIN, and Farzaneh Ahmadpour Ghazvini, “Evaluation of Ovarian Reserve after Laparoscopic Cystectomy for Endometrioma with or without Vasopressin Injection: A Randomized Clinical Trial Study,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 37, no. 514 , pp. 48–54, 2019, [Online]. Available: https://sid.ir/paper/361906/en

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