Effects of Long-Term, High Doses of Nitrate Administration on Adiposity Index in Female Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JEDDI S.; BAKHTIARZADEH F.; GHEIBI S.; GHASEMI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM) Year:2018 | Volume:20 | Issue:5 Page(s): 253-262

Download Full-Text

Persian Verion

View:

244

Download:

Cites:

Information Journal Paper

Title

Effects of Long-Term, High Doses of Nitrate Administration on Adiposity Index in Female Rats

Author(s)

JEDDI S. | BAKHTIARZADEH F. | GHEIBI S. | GHASEMI A. | Issue Writer Certificate

Keywords

ObesityQ2

NitrateQ2

Nitric oxideQ2

Adiposity indexQ1

Abstract

Introduction: Despite higher prevalence of Obesity in women, the anti-Obesity effects of Nitrate have mostly been studied in male animals, using low doses of Nitrate for short durations. This study aims at determining effects of long-term (6 months), administration of high doses of Nitrate on the Obesity indices of normal adult female rats. Materials and Methods: Female Wistar rats were divided into 3 groups (n=10/group): Control group received tap water and the two treatment groups received water containing 250 and 500 mg/L sodium Nitrate for 6 months. Body weight, food intake, and water consumption were measured weekly. Naso-anal length, body mass index (BMI), Lee index, as well as abdominal and thoracic circumferences were determined every two months. Weights of white adipose tissue (WAT) and brown adipose tissue (BAT) were measured at the end of study and Adiposity index was calculated. Results: Administration of Nitrate had no effect on food intake but significantly (p<0. 001) increased water consumption in female rats. Compared to the control group, there was no significant difference in body weight and nasal-to-anal length in the Nitrate-treated rats. At the end of study, compared to controls, in Nitrate-treated rats, BMI (23%), Lee index (7%), Adiposity index (36%), weight of WAT as well as abdominal (5%) and thoracic (6%) circumferences were significantly lower. Weight of BAT was also significantly higher in the interscapular region, i. e 0. 23± 0. 02, 0. 39± 0. 03 and 0. 32± 0. 02 gram in the control and Nitrate groups (250 and 500 mg/L), respectively. and in the axillary region 0. 24± 0. 03, 0. 33± 0. 02 and 0. 30± 0. 03 gram in the control and Nitrate groups (250 and 500 mg/L), respectively. Conclusion: Nitrate administration prevents increase in adiposity in normal adult female rats, beneficial effects which may be associated with increased browning of WAT.

Cites

No record.

References

No record.

Cite

APA: Copy

JEDDI, S., BAKHTIARZADEH, F., GHEIBI, S., & GHASEMI, A.. (2018). Effects of Long-Term, High Doses of Nitrate Administration on Adiposity Index in Female Rats. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 20(5 ), 253-262. SID. https://sid.ir/paper/362318/en

Vancouver: Copy

JEDDI S., BAKHTIARZADEH F., GHEIBI S., GHASEMI A.. Effects of Long-Term, High Doses of Nitrate Administration on Adiposity Index in Female Rats. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2018;20(5 ):253-262. Available from: https://sid.ir/paper/362318/en

IEEE: Copy

S. JEDDI, F. BAKHTIARZADEH, S. GHEIBI, and A. GHASEMI, “Effects of Long-Term, High Doses of Nitrate Administration on Adiposity Index in Female Rats,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 20, no. 5 , pp. 253–262, 2018, [Online]. Available: https://sid.ir/paper/362318/en

Related Journal Papers