Evaluation of the Relation between Serum Level of High-Sensitivity Reactive Protein (HS-CRP) and Coronary Calcification with the Presence of Coronary Artery Disease in Computed Tomography Angiography

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Sajjadieh Amirreza; Arefpour Alireza

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Journal: Journal of Isfahan Medical School Year:2019 | Volume:37 | Issue:531 Page(s): 673-679

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Information Journal Paper

Title

Evaluation of the Relation between Serum Level of High-Sensitivity Reactive Protein (HS-CRP) and Coronary Calcification with the Presence of Coronary Artery Disease in Computed Tomography Angiography

Author(s)

Sajjadieh Amirreza | Arefpour Alireza | Issue Writer Certificate

Keywords

C-reactive proteinQ2

Vascular calcificationQ1

Coronary diseaseQ3

Computed tomography angiographyQ2

Abstract

Background: Some studies showed that two factors of calcium score and high-sensitivity C-reactive protein (HS-CRP) are related with coronary artery disease, but no definitive theory has been provided. The aim of this study was to determine the relationship between serum level of HS-CRP and calcium score with coronary artery disease. Methods: In a cross-sectional study, 200 patients who were candidates for computed tomography (CT) angiography were studied. The level of HS-CRP and coronary artery calcium scores were measured and their correlation with the intensity of coronary artery disease were evaluated. Findings: There was a direct and significant correlation between calcium score and HS-CRP level (r = 0. 25, P < 0. 001). Multivariate analyzes showed that the odds ratio of coronary artery disease was 3. 5 fold more for male sex, 3. 7 fold for smokers, 7. 6 fold for positive family history, 5. 8 fold for high blood pressure, 1. 4 fold for calcium scores, 11. 8 f fold or high HS-CRP, 1. 8 fold for hyperlipidemia. Conclusion: Our results show that HS-CRP level in patients with coronary artery disease is higher than those without coronary artery disease, and there is a direct and significant correlation between this index and calcium scores. HS-CRP seems to be a good indicator for predicting the risk of Coronary disease. At the same time, further studies in this field are suggested.

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APA: Copy

Sajjadieh, Amirreza, & Arefpour, Alireza. (2019). Evaluation of the Relation between Serum Level of High-Sensitivity Reactive Protein (HS-CRP) and Coronary Calcification with the Presence of Coronary Artery Disease in Computed Tomography Angiography. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 37(531 ), 673-679. SID. https://sid.ir/paper/362564/en

Vancouver: Copy

Sajjadieh Amirreza, Arefpour Alireza. Evaluation of the Relation between Serum Level of High-Sensitivity Reactive Protein (HS-CRP) and Coronary Calcification with the Presence of Coronary Artery Disease in Computed Tomography Angiography. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2019;37(531 ):673-679. Available from: https://sid.ir/paper/362564/en

IEEE: Copy

Amirreza Sajjadieh, and Alireza Arefpour, “Evaluation of the Relation between Serum Level of High-Sensitivity Reactive Protein (HS-CRP) and Coronary Calcification with the Presence of Coronary Artery Disease in Computed Tomography Angiography,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 37, no. 531 , pp. 673–679, 2019, [Online]. Available: https://sid.ir/paper/362564/en

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