COMPARISON OF THE EFFICACY OF ORAL (10 &15 MG/KG) AND RECTAL (15 MG/KG) ACETAMINOPHEN IN FEVER REDUCTION IN CHILDREN

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GOLESTAN M.; AMIRI A.; AKHAVAN KARBASI S.; SADR BAFGHI S.M.; MODARES MOSADEGH M.

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2005 | Volume:13 | Issue:3 Page(s): 3-3

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Title

COMPARISON OF THE EFFICACY OF ORAL (10 &15 MG/KG) AND RECTAL (15 MG/KG) ACETAMINOPHEN IN FEVER REDUCTION IN CHILDREN

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Keywords

RECTAL ACETAMINOPHENQ4

ORAL ACETAMINOPHENQ4

FEVER.Q4

Abstract

Introduction: FEVER.is the most common symptom of patients referring to pediatrics clinics.. The first choice for antipyretic medication is acetaminophen with dosage of 10-15 mg/kg every 4-6 hours. We compared the efficacy of oral (10 &15 mg/kg) and rectal (15 mg/kg) acetaminophen in FEVER.reduction in children Methods: A randomized, controlled trial was performed in 90 patients aged between 6months and 6 years with FEVER.> 39o Celsius. The patients were divided into three groups; Group 1 administerd rectal acetaminophen 15mg/kg, Group2 ORAL ACETAMINOPHEN 15mg/kg and Group3 ORAL ACETAMINOPHEN 10mg/kg. The results at the end of the first and third hour were assessed. Results: The rate of temperature reduction at the end of the first and third hour in the group receiving rectal acetaminophen (15mg/kg) was 1.07 +0.16 and 1/74 + 0.25, respectively. The rate of temperature at the end of the first and third hour in the group receiving ORAL ACETAMINOPHEN (15mg/kg) was 0.98 + 0.19 and 1.25 and 1.7+0.14, respectively The rate of temperature reduction at the end of the first and third hour in the group receiving ORAL ACETAMINOPHEN (10mg/kg) was 0.63 +0.18 and 1.25+ 0.22, respectively Conclusion: There was no significant difference in temperature reduction between the groups receiving oral (15mg/kg) and RECTAL ACETAMINOPHEN, but ORAL ACETAMINOPHEN (10 mg/kg) was less effective in temperature reduction.

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APA: Copy

GOLESTAN, M., AMIRI, A., AKHAVAN KARBASI, S., SADR BAFGHI, S.M., & MODARES MOSADEGH, M.. (2005). COMPARISON OF THE EFFICACY OF ORAL (10 &15 MG/KG) AND RECTAL (15 MG/KG) ACETAMINOPHEN IN FEVER REDUCTION IN CHILDREN. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 13(3), 3-3. SID. https://sid.ir/paper/36265/en

Vancouver: Copy

GOLESTAN M., AMIRI A., AKHAVAN KARBASI S., SADR BAFGHI S.M., MODARES MOSADEGH M.. COMPARISON OF THE EFFICACY OF ORAL (10 &15 MG/KG) AND RECTAL (15 MG/KG) ACETAMINOPHEN IN FEVER REDUCTION IN CHILDREN. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;13(3):3-3. Available from: https://sid.ir/paper/36265/en

IEEE: Copy

M. GOLESTAN, A. AMIRI, S. AKHAVAN KARBASI, S.M. SADR BAFGHI, and M. MODARES MOSADEGH, “COMPARISON OF THE EFFICACY OF ORAL (10 &15 MG/KG) AND RECTAL (15 MG/KG) ACETAMINOPHEN IN FEVER REDUCTION IN CHILDREN,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 13, no. 3, pp. 3–3, 2005, [Online]. Available: https://sid.ir/paper/36265/en

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