Introduce Characteristic, Types and Functional Mechanism of Adjuvants as a Biologic Complement

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Zarei Taher T.; KOWSARI A.; SHEYKHHASAN M.; MANOOCHEHRI H.; KALHOR N.; Naserpour L.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ADVANCED BIOMEDICAL SCIENCES Year:2020 | Volume:9 | Issue:4 Page(s): 1758-1773

Download Full-Text

Persian Verion

View:

2,406

Download:

Cites:

Information Journal Paper

Title

Introduce Characteristic, Types and Functional Mechanism of Adjuvants as a Biologic Complement

Author(s)

Keywords

adjuvantsQ2

characteristicsQ2

mechanismQ2

functionQ3

Abstract

The widespread use of effective vaccines against infectious diseases has been one of the most important public health progresses in the 21st century. Early vaccines containing weakened or inactivated pathogens or toxins may elicit robust, protective immune responses, but this approach cannot always be used because it is impractical and inefficient to culture large numbers of organisms, and lack of safety. In such cases subunits (e. g., microbial proteins or carbohydrate) are being considered as vaccine antigens. Since the subtypes of antigens often have weak immunogenic properties, they cannot stimulate the innate immune system. This property is probably the cause of the reduced efficacy of the vaccine. adjuvants are molecules, compounds, or supramolecular complexes that boost the potency and longevity of specific immune response to antigens, but can cause minimal toxicity or long-lasting immune effects on human. adjuvants can be used to enhance immunogenicity, modulate the type of immune response, reduce the amount of antigen or the number of immunizations required for efficacy, and/or improve the efficacy of vaccines in specific populations (e. g., newborns or elderly). The present paper reviews the different types of adjuvants and examines the characteristics and mechanisms of their performance.

Cites

No record.

References

Cite

APA: Copy

Zarei Taher, T., KOWSARI, A., SHEYKHHASAN, M., MANOOCHEHRI, H., KALHOR, N., & Naserpour, L.. (2020). Introduce Characteristic, Types and Functional Mechanism of Adjuvants as a Biologic Complement. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, 9(4 ), 1758-1773. SID. https://sid.ir/paper/363356/en

Vancouver: Copy

Zarei Taher T., KOWSARI A., SHEYKHHASAN M., MANOOCHEHRI H., KALHOR N., Naserpour L.. Introduce Characteristic, Types and Functional Mechanism of Adjuvants as a Biologic Complement. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES[Internet]. 2020;9(4 ):1758-1773. Available from: https://sid.ir/paper/363356/en

IEEE: Copy

T. Zarei Taher, A. KOWSARI, M. SHEYKHHASAN, H. MANOOCHEHRI, N. KALHOR, and L. Naserpour, “Introduce Characteristic, Types and Functional Mechanism of Adjuvants as a Biologic Complement,” JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, vol. 9, no. 4 , pp. 1758–1773, 2020, [Online]. Available: https://sid.ir/paper/363356/en

Related Journal Papers