DIAGNOSTIC VALUE OF PROLACTIN AND B-HCG LEVELS OF VAGINAL FLUID IN DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANES

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TAHERIPANAH R.; DAVOUDI ZOHREH; ENTEZARI ABAS; HOSSEINI MARYAM AL SADAT; KHODAKARAMI N.

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2009 | Volume:17 | Issue:4 (67) Page(s): 234-241

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Title

DIAGNOSTIC VALUE OF PROLACTIN AND B-HCG LEVELS OF VAGINAL FLUID IN DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANES

Author(s)

Keywords

PREMATURE RUPTURE OF MEMBRANESQ3

PROLACTINQ3

B-HCGQ3

FERN TESTQ3

NITRAZINQ3

Abstract

Introduction: The aim of this study was diagnosis of PREMATURE RUPTURE OF MEMBRANES in suspected patients by measurement of PROLACTIN and B-HCG levels in vaginal washing in order to reduce perinatal mortality and morbidity.Methods: The study included 211 pregnant women who were referred to the emergency of Imam Hossein hospital at 28-38 weeks of pregnancy for leakage or prenatal care from April, 2007 to April, 2008. The expulsion of fluid from the cervix was evaluated and fern and NITRAZIN tests were done. B-HCG and PROLACTIN levels of vaginal washing fluid were measured. The presence of 2 of 3 parameters of FERN TEST, NITRAZIN and cervical fluid was defined as absolutely PREMATURE RUPTURE OF MEMBRANES. Mann-Withney U-test was used for analysis. The Roc curve was calculated.Results: There were 132 patients in PROM group and79 patient in the control group. The average age in the PROM and control groups was 26.9±6.08 and 26.2±4.84 years, respectively (P=0.074). Both groups were matched for parity and gravidity. PROLACTIN levels in PROM group were 2930±3737mIU/l versus 23.18±120mIU/l in the control group (P=0.000). B-HCG was 439.78±1867mIU/l in PROM and 17.72±30mIU/l in control group (p=0.000). Sensitivity and specificity of PROLACTIN according to cut-off of 16.0 mIU/l was 79.41% and 96%, respectively. Sensitivity and specificity for B-HCG with cut-off point of 12.5 was 69.85% and 69.33%, respectively.Conclusion: The measurement of PROLACTIN and B-HCG levels in patients with suspected PREMATURE RUPTURE OF MEMBRANES can help in decision-making and treatment.

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References

PRACTICABILITY OF VAGINAL FLUID ALFA- FETOPROTEIN AND CREATININ LEVELS FOR DETECTING PREMATURE RUPTURE OF MEMBRANES

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APA: Copy

TAHERIPANAH, R., DAVOUDI, ZOHREH, ENTEZARI, ABAS, HOSSEINI, MARYAM AL SADAT, & KHODAKARAMI, N.. (2009). DIAGNOSTIC VALUE OF PROLACTIN AND B-HCG LEVELS OF VAGINAL FLUID IN DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANES. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 17(4 (67)), 234-241. SID. https://sid.ir/paper/36448/en

Vancouver: Copy

TAHERIPANAH R., DAVOUDI ZOHREH, ENTEZARI ABAS, HOSSEINI MARYAM AL SADAT, KHODAKARAMI N.. DIAGNOSTIC VALUE OF PROLACTIN AND B-HCG LEVELS OF VAGINAL FLUID IN DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANES. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;17(4 (67)):234-241. Available from: https://sid.ir/paper/36448/en

IEEE: Copy

R. TAHERIPANAH, ZOHREH DAVOUDI, ABAS ENTEZARI, MARYAM AL SADAT HOSSEINI, and N. KHODAKARAMI, “DIAGNOSTIC VALUE OF PROLACTIN AND B-HCG LEVELS OF VAGINAL FLUID IN DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANES,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 4 (67), pp. 234–241, 2009, [Online]. Available: https://sid.ir/paper/36448/en

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