Determination of TraT Gene in Isolated Escherichia Coli Isolated from Patients Referred to Abadan Hospitals During 2017-2018

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Baghban Z.; VALIZADEH Z.

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Journal: Armaghane Danesh Year:2019 | Volume:24 | Issue:2 (133) Page(s): 238-246

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Title

Determination of TraT Gene in Isolated Escherichia Coli Isolated from Patients Referred to Abadan Hospitals During 2017-2018

Author(s)

Baghban Z. | VALIZADEH Z. | Issue Writer Certificate

Keywords

Escherichia coliQ2

traT geneQ1

Urinary tract infectionQ3

Antibiotic resistanceQ2

Abstract

Background & aim: Escherichia coli is one of the most important causes agents of Urinary tract infection in human. Thus, identification of Escherichia coli resistance patterns seems to be necessary. traT gene has been reported variable in E. coli strains isolated from Urinary tract infection. The aim of this study was to investigate the prevalence of uropathogenic E. coli and detection of traT gene in isolated from patients referred to Abadan hospitals. Methods: In this experimental study, 138 urine specimens were collected from patients suffering from Urinary tract infection in Abadan hospitals and medical centers during 2017-2018. A number of100 E. coli strains were identified using microbiological and biochemical tests. The drug sensitivity definition test was done by PCR method. The collected data were analyzed by one-way ANOVA and T-test. Result: Among isolates isolated from E. coli, 15 isolates were resistant to all used antibiotics. The highest resistance rates of E. coli isolates to Nalidixic acid and Tetracycline were 92% and 91%, respectively. The least resistance was observed for Nitrofurantoin and Cefoxitin (23% and 24%). Also, in 11 isolates, the presence of traT gene was confirmed; therefore, the prevalence of the traT gene was 73. 33% Conclusion: Based on the results, the traT virulence gene was highly prevalent among strains isolated from Abadan hospitals. Therefore, traT gene could be considered as a therapeutic target in the future.

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APA: Copy

Baghban, Z., & VALIZADEH, Z.. (2019). Determination of TraT Gene in Isolated Escherichia Coli Isolated from Patients Referred to Abadan Hospitals During 2017-2018. ARMAGHAN DANESH, 24(2 (133) ), 238-246. SID. https://sid.ir/paper/365281/en

Vancouver: Copy

Baghban Z., VALIZADEH Z.. Determination of TraT Gene in Isolated Escherichia Coli Isolated from Patients Referred to Abadan Hospitals During 2017-2018. ARMAGHAN DANESH[Internet]. 2019;24(2 (133) ):238-246. Available from: https://sid.ir/paper/365281/en

IEEE: Copy

Z. Baghban, and Z. VALIZADEH, “Determination of TraT Gene in Isolated Escherichia Coli Isolated from Patients Referred to Abadan Hospitals During 2017-2018,” ARMAGHAN DANESH, vol. 24, no. 2 (133) , pp. 238–246, 2019, [Online]. Available: https://sid.ir/paper/365281/en

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