Determining Difference in Evolutionary Variation of Bacterial RecA Proteins vs 16SrRNA Genes Using 16S-Toxonomy Tree

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Maleki Avisa; FAHIMI HOSSEIN; TAGHIZADEH MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY Year:2019 | Volume:13 | Issue:1 Page(s): 32-43

Download Full-Text

Persian Verion

View:

596

Download:

Cites:

Information Journal Paper

Title

Determining Difference in Evolutionary Variation of Bacterial RecA Proteins vs 16SrRNA Genes Using 16S-Toxonomy Tree

Author(s)

Maleki Avisa | FAHIMI HOSSEIN | TAGHIZADEH MOHAMMAD | Issue Writer Certificate

Keywords

Taxonomy treeQ1

Bacterial RecA protein familyQ1

16SrRNA geneQ1

16S-taxonomy treeQ1

Drug resistanceQ3

Abstract

Background and Aims: The rate of variation in various genes of a bacterial species is different during evolution. Therefore, in systematic bacterial studies many researchers compare the phylogenetic tree of a particular gene to the standard tree of an rRNA gene. Regarding the importance of 16SrRNA gene and the evolutionary process of RecA protein family, we investigated the changes in sequences of the RecA protein family in selected bacterial phylums in comparing with their 16SrRNA genes. Materials and Methods: For this purpose, sequences of the RecA protein family were extracted from Uniprot database (with some help from ProSite) and then they were categorized by using CD-hit algorithm. One species was selected from each category. Then we found 16SrRNA complete sequences for same species. After that, based on the Average Alignment Score (AAS), the 16S-taxonomic tree was obtained. Furthermore, Similar calculations were considered for corresponding RecA proteins phylums. Results: By comparing amount of AAS in 16SrRNA phylums and RecA phylums, we observed that the Actinobacteria phylum is the closest to the header phylum in the 16STaxonomy tree, but this phylum in the RecA is the most distant to the header phylum, on the other hand, the position of the cyanobacteria phylum remains the same in both calculations, which indicates the least amount of changes in the genus and species of this phylum. Conclusion: The 16S-Taxonomy tree which has been compiled and presented in this study for the first time is different from the available bioinformatics algorithms for phylogenetic tree drawing. Finding the species with the highest and lowest rates of changes, can be a type of prediction method for indicating the reasons why bacteria become resistant to drugs over a long period of time.

Cites

Quantitative Comparison of Tree Pairs Resulted from Gene and Protein Phylogenetic Trees for Sulfite Reductase Flavoprotein Alpha-Component and 5S rRNA and Taxonomic Trees in Selected Bacterial Species

References

Careful Use of 16S rRNA Gene Sequence Similarity Values for the Identification of Mycobacterium Species

Cite

APA: Copy

Maleki, Avisa, FAHIMI, HOSSEIN, & TAGHIZADEH, MOHAMMAD. (2019). Determining Difference in Evolutionary Variation of Bacterial RecA Proteins vs 16SrRNA Genes Using 16S-Toxonomy Tree. IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY, 13(1 ), 32-43. SID. https://sid.ir/paper/365370/en

Vancouver: Copy

Maleki Avisa, FAHIMI HOSSEIN, TAGHIZADEH MOHAMMAD. Determining Difference in Evolutionary Variation of Bacterial RecA Proteins vs 16SrRNA Genes Using 16S-Toxonomy Tree. IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY[Internet]. 2019;13(1 ):32-43. Available from: https://sid.ir/paper/365370/en

IEEE: Copy

Avisa Maleki, HOSSEIN FAHIMI, and MOHAMMAD TAGHIZADEH, “Determining Difference in Evolutionary Variation of Bacterial RecA Proteins vs 16SrRNA Genes Using 16S-Toxonomy Tree,” IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY, vol. 13, no. 1 , pp. 32–43, 2019, [Online]. Available: https://sid.ir/paper/365370/en

Related Journal Papers