THE RISK FACTORS FOR GDM AND THE VALUE OF THE SCREENING TEST

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KESHAVARZ M.; BABAEI GH.R.

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Paper Information

Journal: IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM) Year:2005 | Volume:6 | Issue:4 (SN 24) Page(s): 0-0

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Title

THE RISK FACTORS FOR GDM AND THE VALUE OF THE SCREENING TEST

Author(s)

KESHAVARZ M. | BABAEI GH.R. | Issue Writer Certificate

Keywords

RISK FACTORS OF GESTATIONAL DIABETESQ4

SCREENING TESTQ4

SENSITIVITYQ3

SPECIFICITYQ3

POSITIVE AND NEGATIVE PREDICTIVE VALUEQ4

Abstract

Introduction: The RISK FACTORS OF GESTATIONAL DIABETES mellitus (GDM) associated have been largely derived from populations of European extraction, and there are few studies examining this issue in Iran. According the ADA recommendation the cut- off point of SCREENING TEST with 50 gr glucose to 130 mg/dL has been decreased, So this study was conducted to determine of the risk factors of GDM in Iranian pregnant women of Shahrood city and comparison the value of SCREENING TEST with two different cut off points (130 and 140 mg/dL). Materials and Methods: In a general screening for 1310 pregnant women referring to the Fatemiyeh Hospital, 12 risk factors were considered at the first screening. On the other in order to determine the value of the SCREENING TEST without taking into account the results of the initial SCREENING TEST, the OGTT was done with 100 gr oral glucose for the first 459 pregnant women. All measurements of serum glucose were performed by the glucose oxidase method at the Fatemiyeh Hospital Laboratory. Results: According to the Logistic model, the most important of risk factors included: Glucosuria, previous macrosomia, obesity, family history of diabetes, age ≥ 30 yr and previous unknown neonate’s death. Glucosuria had the highest odds ratio (OR=41.7,CI=15.7-110.3,P<0/001) and positive predictive value (P.P.V) (63%) and the lowest odds ratio was related to age ≥ 30yr (OR=3, CI=1.8-5, P<0/001). A SENSITIVITY of 97%, SPECIFICITY of 81%, P.P.V of 27% and a negative predictive value N.P.V of 99.7% of GCT 50gr were determined with a 130 mg/dL cut off point and a SENSITIVITY of 85%, SPECIFICITY of 88%, a P.P.V of 35% and N.P.V of 99% with a 140 mg/dL cut off point. Conclusion: Recognized risk factors of GDM were valid for our population. Use of 130 mg/dL as a cut off point in the SCREENING TEST demonstrated a higher N.P.V and SENSITIVITY, indicating this to be a better cut off point for diagnosis of women with GDM.

Cites

FREQUENCY OF GESTATIONAL DIABETES AND ITS RELATED FACTORS IN PREGNANT WOMEN IN PRENATAL CLINICS OF EDUCATIONAL HOSPITALS, IN TEHRAN (OCT 2000-MARCH 2002)

References

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APA: Copy

KESHAVARZ, M., & BABAEI, GH.R.. (2005). THE RISK FACTORS FOR GDM AND THE VALUE OF THE SCREENING TEST. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 6(4 (SN 24)), 0-0. SID. https://sid.ir/paper/365777/en

Vancouver: Copy

KESHAVARZ M., BABAEI GH.R.. THE RISK FACTORS FOR GDM AND THE VALUE OF THE SCREENING TEST. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2005;6(4 (SN 24)):0-0. Available from: https://sid.ir/paper/365777/en

IEEE: Copy

M. KESHAVARZ, and GH.R. BABAEI, “THE RISK FACTORS FOR GDM AND THE VALUE OF THE SCREENING TEST,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 6, no. 4 (SN 24), pp. 0–0, 2005, [Online]. Available: https://sid.ir/paper/365777/en

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