The Effect of Bacteriophages against Gram-Negative Bacteria Infections in Vivo: A Systematic Review

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RAHIMZADEH GOLNAR; FARSHIDI FERESHTEH; Sadegh Rezai Mohammad; Rezai Shaghayegh

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Journal: Journal of Isfahan Medical School Year:2019 | Volume:37 | Issue:524 Page(s): 427-434

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Title

The Effect of Bacteriophages against Gram-Negative Bacteria Infections in Vivo: A Systematic Review

Author(s)

RAHIMZADEH GOLNAR | FARSHIDI FERESHTEH | Sadegh Rezai Mohammad | Rezai Shaghayegh | Issue Writer Certificate

Keywords

BacteriophageQ1

Gram-negative bacteriaQ1

InfectionQ3

Systematic reviewQ1

Abstract

Background: Infections caused by multidrug-resistant (MDR) Gram-negative bacteria are rising. Bacteriophages are suggested as an alternative treatment option for the treatment of antibiotic-resistant bacteria. Bacteriophages in treatment of Gram-negative bacterial Infections is not well investigated in vivo. The aim of this study was to review systematically the studies on Bacteriophages against Infection caused by Gram-negative bacteria in vivo. Methods: This Systematic review was done using electronic databases, including Scopus, PubMed, Google Scholar, and Web of science; the articles published from 1983 to 2018 were investigated. Studies meeting the inclusion criteria were selected, and the data were estimated using a review method. Findings: 1310 articles were indexed from which 380 were selected based on their abstracts. Then, some were excluded including clinical trials and in-vitro studies. Finally, experimental studies (n = 31), that met the inclusion criteria and were published in English, were selected. Conclusion: This review showed that Bacteriophages are an effective treatment against n-vivo Gram-negative bacteria Infections even be used orally, topically, or subcutaneously injected.

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APA: Copy

RAHIMZADEH, GOLNAR, FARSHIDI, FERESHTEH, Sadegh Rezai, Mohammad, & Rezai, Shaghayegh. (2019). The Effect of Bacteriophages against Gram-Negative Bacteria Infections in Vivo: A Systematic Review. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 37(524 ), 427-434. SID. https://sid.ir/paper/365887/en

Vancouver: Copy

RAHIMZADEH GOLNAR, FARSHIDI FERESHTEH, Sadegh Rezai Mohammad, Rezai Shaghayegh. The Effect of Bacteriophages against Gram-Negative Bacteria Infections in Vivo: A Systematic Review. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2019;37(524 ):427-434. Available from: https://sid.ir/paper/365887/en

IEEE: Copy

GOLNAR RAHIMZADEH, FERESHTEH FARSHIDI, Mohammad Sadegh Rezai, and Shaghayegh Rezai, “The Effect of Bacteriophages against Gram-Negative Bacteria Infections in Vivo: A Systematic Review,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 37, no. 524 , pp. 427–434, 2019, [Online]. Available: https://sid.ir/paper/365887/en

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