The Preventive Effects of Aminophylline, Metoclopramide, and Acetaminophen on Postoperative Pain after Strabismus Surgery; A Randomized Clinical Trial Study

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MORADI FARSANI DARIOUSH; Heidari Sayed Morteza; Piri Behruz

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Journal: Journal of Isfahan Medical School Year:2019 | Volume:37 | Issue:548 Page(s): 1185-1191

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Title

The Preventive Effects of Aminophylline, Metoclopramide, and Acetaminophen on Postoperative Pain after Strabismus Surgery; A Randomized Clinical Trial Study

Author(s)

MORADI FARSANI DARIOUSH | Heidari Sayed Morteza | Piri Behruz | Issue Writer Certificate

Keywords

AminophyllineQ2

MetoclopramideQ2

AcetaminophenQ3

StrabismusQ3

Abstract

Background: There are many drugs to control the pain after surgeries. Aminophylline, Metoclopramide, and Acetaminophen are known to be able to control pain. In this study, we aimed to compare the effects of these three drugs in controlling pain after Strabismus correction surgery. Methods: This was a double-blinded randomized clinical trial on 120 patients underwent Strabismus correction surgery in Feiz hospital, Isfahan, Iran. Patients were randomized into 4 groups of Aminophylline, Metoclopramide, Acetaminophen, and placebo. All patients and surgeons were unaware of groups and drugs. After Strabismus surgery, patients were assessed using visual analogue scale (VAS) to evaluate their pain. Hemodynamic parameters, as well as extubation and recovery times after surgeries were also evaluated. Findings: Postoperative pain assessments indicated a lower pain intensity in Acetaminophen, Metoclopramide, and Aminophylline, respectively, compared to placebo at the time of recovery entrance and 15 and 30 minutes afterwards (P < 0. 001). Conclusion: According to the results of present study, Acetaminophen has a better effect in controlling postoperative pain than Metoclopramide and Aminophylline.

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APA: Copy

MORADI FARSANI, DARIOUSH, Heidari, Sayed Morteza, & Piri, Behruz. (2019). The Preventive Effects of Aminophylline, Metoclopramide, and Acetaminophen on Postoperative Pain after Strabismus Surgery; A Randomized Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 37(548 ), 1185-1191. SID. https://sid.ir/paper/366760/en

Vancouver: Copy

MORADI FARSANI DARIOUSH, Heidari Sayed Morteza, Piri Behruz. The Preventive Effects of Aminophylline, Metoclopramide, and Acetaminophen on Postoperative Pain after Strabismus Surgery; A Randomized Clinical Trial Study. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2019;37(548 ):1185-1191. Available from: https://sid.ir/paper/366760/en

IEEE: Copy

DARIOUSH MORADI FARSANI, Sayed Morteza Heidari, and Behruz Piri, “The Preventive Effects of Aminophylline, Metoclopramide, and Acetaminophen on Postoperative Pain after Strabismus Surgery; A Randomized Clinical Trial Study,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 37, no. 548 , pp. 1185–1191, 2019, [Online]. Available: https://sid.ir/paper/366760/en

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